42104-58-5Relevant academic research and scientific papers
Nanomolar inhibitors of the transcription factor STAT5b with high selectivity over STAT5a
Elumalai, Nagarajan,Berg, Angela,Natarajan, Kalaiselvi,Scharow, Andrej,Berg, Thorsten
, p. 4758 - 4763 (2015/04/14)
Src homology 2 (SH2) domains play a central role in signal transduction. Although many SH2 domains have been validated as drug targets, their structural similarity makes development of specific inhibitors difficult. The cancer-relevant transcription facto
Rapid one-pot synthesis of alkane-α ω, diylbisphosphonic acids from dihalogenoalkanes under microwave irradiation
Villemin, Didier,Moreau, Bernard,Kaid, M'Hamed,Didi, Mohamed Amine
experimental part, p. 1583 - 1586 (2010/10/01)
A one-pot, two-step synthesis of alkylenebisphosphonic acids from dihalogenoalkanes was performed under microwave irradiation. The reaction is very rapid and convenient for the synthesis of small samples of alkylenebisphosphonic acids. Copyright Taylor & Francis Group, LLC.
Phosphonic acid derivatives useful as anti-inflammatory agents
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, (2008/06/13)
Novel 1,2-oxaphosphepins are useful as antiinflammatory and antiarthritic agents. A representative oxaphosphepin is 3,4-dihydro-3-methoxy-7-(phenylmethoxy)-1H-naphth[1,8de][1,2]oxaphosphepin-3-oxide.
(o-Hydroxyphenyl)methylphosphonic acids: Synthesis and Potentiometric Determinations of their pKa Values
Boehmer, Volker,Vogt, Walter,Chafaa, Salah,Meullemeestre, Jean,Schwing, Marie-Jose,Vierling, Francois
, p. 139 - 149 (2007/10/02)
(o-Hydroxyphenyl)methylphosphonic acids are readily obtained from o-(bromomethyl)- or o-(hydroxymethyl)phenols and trialkyl phosphites.Subsequent hydrolysis leads to the corresponding phosphonic acids.For a series of such compounds, the pKa val
