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Quinacrine mustard dihydrochloride is a fluorescent DNA-intercalating agent that selectively binds to adenine-thymine (AT) base pairs over guanine-cytosine (GC) base pairs. It has been used to label metaphase chromosomes for karyotyping by autoradiography, with excitation/emission maxima of 425/480 nm, respectively.

4213-45-0

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4213-45-0 Usage

Uses

Used in Biotechnology and Research Applications:
Quinacrine mustard dihydrochloride is used as a fluorescent probe for visualizing and analyzing DNA structures, particularly in the study of chromosomes during karyotyping. Its selective binding to AT base pairs and fluorescence properties make it a valuable tool in genetic research and diagnostics.
Used in Medical Diagnostics:
In the medical diagnostics industry, quinacrine mustard dihydrochloride serves as a fluorescent stain to aid in the identification and analysis of chromosomal abnormalities. Its ability to bind specifically to AT-rich regions of DNA enhances the visualization of chromosome banding patterns, which is crucial for diagnosing genetic disorders and understanding the mechanisms of disease.

Safety Profile

Questionable carcinogen with experimental neoplastigenic data. Human mutation data reported. Corrosive. When heated to decomposition it emits very toxic fumes of Cland NOx. See also QUINACRINE MUSTARD.

Check Digit Verification of cas no

The CAS Registry Mumber 4213-45-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,1 and 3 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 4213-45:
(6*4)+(5*2)+(4*1)+(3*3)+(2*4)+(1*5)=60
60 % 10 = 0
So 4213-45-0 is a valid CAS Registry Number.
InChI:InChI=1/C23H28Cl3N3O/c1-16(4-3-11-29(12-9-24)13-10-25)27-23-19-7-5-17(26)14-22(19)28-21-8-6-18(30-2)15-20(21)23/h5-8,14-16H,3-4,9-13H2,1-2H3,(H,27,28)

4213-45-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name quinacrine mustard dihydrochloride

1.2 Other means of identification

Product number -
Other names Quinacrine mustard dihydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4213-45-0 SDS

4213-45-0Upstream product

4213-45-0Downstream Products

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