421553-87-9Relevant academic research and scientific papers
One-pot preparation of 1,2-aminoalcohols or pyrroles by CeCl3·7 H2O-mediated Barbier reactions of N,N'-bis[(S)-1-phenylethyl]ethanediimine
Martelli,Morri,Savoia
, p. 158 - 160 (2002)
1,2-Aminoalcohols or pyrroles were obtained from N,N′-bis[(S)-1-phenylethyl]ethanediimine by a one-pot procedure involving two Barbier additions of allylic and/or propargyl zinc reagents alternated with the hydrolysis of the unreacted imine function, followed by a cyclisation/dehydration sequence when a 1-amino-5-pentyne moiety was involved, all these steps being promoted by CeCl3·7 H2O.
