421580-53-2 Usage
Uses
Used in Pharmaceutical Industry:
N-(2-[(5-CHLORO-2-METHOXYPHENYL)AMINO]-4'-METHYL-4,5'-BI-1,3-THIAZOL-2'-YL)BENZAMIDE is used as a therapeutic agent for the treatment of cystic fibrosis, specifically targeting the CFTR ΔF508 mutation. It works by rescuing and correcting the folding defect of the CFTR ΔF508 mutant, promoting proper trafficking, glycosylation, and surface expression in cells. This leads to enhanced folding efficiency, delayed ER-associated degradation, and increased stability of the mutant protein on the plasma membrane, ultimately restoring forskolin-stimulated CFTR activity in affected cells.
Check Digit Verification of cas no
The CAS Registry Mumber 421580-53-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,1,5,8 and 0 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 421580-53:
(8*4)+(7*2)+(6*1)+(5*5)+(4*8)+(3*0)+(2*5)+(1*3)=122
122 % 10 = 2
So 421580-53-2 is a valid CAS Registry Number.
