421598-55-2 Usage
Chemical class
It is a type of trioxolane, which is a class of organic compounds containing a three-membered cyclic peroxide ring.
Structural features
The compound contains tertiary and isopropyl groups.
Potential applications
Trioxolanes, including 1,2,4-Trioxolane,3-(1,1-dimethylethyl)-3-(1-methylethyl)-(9CI), have been investigated for their potential as antimalarial drugs.
Mechanism of action
The antimalarial potential is attributed to their ability to release toxic free radicals when activated by the malaria parasite.
Additional properties
Some trioxolane compounds, including 1,2,4-Trioxolane,3-(1,1-dimethylethyl)-3-(1-methylethyl)-(9CI), have shown promising anticancer and antiparasitic properties.
Research status
Further studies are necessary to fully understand the potential applications and safety of 1,2,4-Trioxolane,3-(1,1-dimethylethyl)-3-(1-methylethyl)-(9CI).
Nomenclature
The compound's name follows the IUPAC nomenclature rules, with the prefix "1,2,4-trioxolane" indicating the presence of a three-membered ring with peroxide linkages, and the substituents "3-(1,1-dimethylethyl)" and "3-(1-methylethyl)" describing the attached groups.
Check Digit Verification of cas no
The CAS Registry Mumber 421598-55-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,1,5,9 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 421598-55:
(8*4)+(7*2)+(6*1)+(5*5)+(4*9)+(3*8)+(2*5)+(1*5)=152
152 % 10 = 2
So 421598-55-2 is a valid CAS Registry Number.
421598-55-2Relevant academic research and scientific papers
Kawamura, Shin-Ichi,Yamakoshi, Hideyuki,Abe, Manabu,Masuyama, Araki,Nojima, Masatomo
, p. 891 - 896 (2002)
Ozonolyses of 1-alkyl-substituted 1-tert-butylethylenes and of highly methylated methylenecycloalkanes were conducted in the presence of trifluoroacetophenone (7) in ether. The ozonolysis of 2,2,6-trimethyl-1-methylenecyclohexane provided only the crossed-ozonide 10 derived from capture of formaldehyde O-oxide with the ketone 7 in 42% yield, while in the case of the relevant 2,2,5-trimethyl-1-methylenecyclopentane the alternative crossed-ozonide 15e derived from cycloaddition of 2,2,5-trimethylcyclopentanone O-oxide with the ketone 7 was the sole isolable product. The total energies of two possible cycloreversion processes for the primary ozonide 12c and for 12e, calculated at B3LYP/6-31G**//B3LYP/3-21G* level of theory, seem to reproduce the observed difference in the regiochemistry of fragmentation between these two primary ozonides.
