42170-02-5Relevant academic research and scientific papers
Straightforward Three-Component Synthesis of N′,N′′-Disubstituted N -Alkyl-1,3,5-Triazinanes
Bunev, Alexander S.,Frontera, Antonio,Grigoriev, Mikhail S.,Grudova, Mariya V.,Kletskov, Alexey V.,Presnukhina, Sofia,Shetnev, Anton,Sinelshchikova, Anna A.,Zaytsev, Vladimir P.,Zubkov, Fedor I.
supporting information, p. 1067 - 1072 (2020/07/04)
Efficient approaches towards the synthesis of various N-substituted 1,3,5-triazinanes based on a transformation of N -alkyl-1,5,3-dioxazepanes or on a domino reaction involving condensation of various amines, amides, and paraformaldehyde are described for the first time. Mg(ClO 4) 2 was shown to be one of the most potent additives for the condensation. The proposed approaches permit the synthesis of a broad spectrum of substituted sym -triazinanes in good yields with relatively easy workup. In the case of the multicomponent reaction, the approach allows the preparation of the target substances from simple and easily accessible reagents. The representatives of the resulting compounds were found to possess no antimicrobial or cytotoxic activity in in vitro bioassays.
Cyclic thioureas as cumene oxidation inhibitors
Garibov,Rzaeva,Shykhaliev,Kuliev,Farzaliev,Allakhverdiev
body text, p. 707 - 711 (2010/08/21)
Hexahydro-1,3,5-triazine-4-thiones were synthesized by ternary condensation of thiourea with various aldehydes and amines. The products were characterized by IR and NMR spectroscopy, and their inhibiting effect on cumene oxidation was examined.
