42198-67-4Relevant academic research and scientific papers
Reduction of α,β unsaturated carbonyl compounds by Ni2+-BH-4
Handique, Jyotirekha G.,Purkayashtha, Arup,Baruah, Jubaraj B.
, p. 90 - 93 (2001)
The reduction of α,β unsaturated carbonyl compounds by sodiumborohydride is catalysed by Ni(bpy)Cl2 (bpy = 2,2′-bipyridine). Various carbonyl compounds having the general formula R1CH=CHCRO [where R1, R = C6H5, H; p-MeO-C6H4-,C6H4; p-CH3-C6H4, C6H5; (m-OMe-)(p-OMe-)C6H3, C6H5; C6H5, (CH3)2CH-; CH3, H; W-Br-C6H4-, C6H5] are reduced to corresponding allylicalcohol [R1CH=CHCRHOH] at 25°C within half an hour. During these reductions the double bond is partially reduced to give saturated alcohols as minor products having the molecular formula R1CH2CH2CRHOH. The reduction of trans-3-phenyl-2-propenal with NaBH4 and catalytic amounts of Ni(bpy)Cl2 in solvents containing active deuterium (D2O, CD3OD), leads to the partial incorporation of deuterium at the α and γ positions to give C-D bonded alcohols.
The Reduction of Substituted Propargyl Alcohols and 3-Butyn-1-ols with Lithium Aluminium Hydride
Kang, Mi Jeong,Jang, Jung-Suk,Lee, Sueg-Geun
, p. 8829 - 8832 (1995)
The LAH reduction of alkyl or aryl substituted propargyl alcohols and 3-butyn-1-ols in diethyl ether and THF have been studied.The unexpected reduction product resulting from the hydride addition to δ-carbon with cis configuration was formed from 4-aryl substituted 3-butyn-1-ols.
