4220-05-7 Usage
Uses
Used in Organic Synthesis:
Trifluoromethionine is utilized as a building block for the creation of complex organic molecules, leveraging its unique properties to enhance the hydrophobicity and metabolic stability of the synthesized compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, trifluoromethionine serves as a key component in the development of novel drugs, particularly for the treatment of various diseases. Its resistance to metabolic enzymes and ability to mimic natural amino acids are crucial for designing drugs with improved efficacy and reduced side effects.
Used in Drug Development:
Trifluoromethionine is employed as a potential therapeutic agent in the development of new medications, capitalizing on its unique chemical properties to target specific biological pathways and mechanisms involved in disease processes.
Used in Protein Structure and Function Studies:
As a mimic of natural amino acids, trifluoromethionine is applied in research to investigate the structure and function of proteins, providing insights into their mechanisms of action and potential modifications for therapeutic intervention.
Despite the promising applications of trifluoromethionine, ongoing research is essential to fully explore its effects and potential uses across different fields, ensuring the safety and efficacy of its incorporation into various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 4220-05-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,2 and 0 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 4220-05:
(6*4)+(5*2)+(4*2)+(3*0)+(2*0)+(1*5)=47
47 % 10 = 7
So 4220-05-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H8F3NO2S/c6-5(7,8)12-2-1-3(9)4(10)11/h3H,1-2,9H2,(H,10,11)/t3-/m0/s1
4220-05-7Relevant articles and documents
A highly active DNA polymerase with a fluorous core
Holzberger, Bastian,Rubini, Marina,Moeller, Heiko M.,Marx, Andreas
, p. 1324 - 1327 (2010)
(Chemical Equation Presented) A multifluorinated DNA polymerase with all 14 methionine residues (Met; red in the structure) globally replaced by the non-natural amino acid trifluoromethionine (TFM) exhibits enzymatic activity and selectivity similar to the wild type. The fluorinated enzyme serves as a 19F NMR probe, and despite its size of 63 kDa, individual 19F resonances allow the study of enzyme dynamics during DNA synthesis by NMR spectroscopy.
