Welcome to LookChem.com Sign In|Join Free
  • or
4-Hydroxymeperidine, also known as 4-HMP, is a chemical compound with the molecular formula C7H13NO2. It is a derivative of meperidine, a synthetic opioid analgesic, and is formed as a metabolite in the human body when meperidine is metabolized. 4-Hydroxymeperidine has been found to have similar pharmacological properties to its parent compound, exhibiting opioid agonist activity. However, it is less potent than meperidine and has a shorter duration of action. The compound has been studied for its potential role in the side effects and toxicity associated with meperidine use, particularly in cases of overdose or long-term administration. Due to its involvement in the metabolism of meperidine, 4-hydroxymeperidine is of interest in the field of drug metabolism and toxicology, as understanding its formation and effects can help in the development of safer and more effective pain management strategies.

4220-06-8

Post Buying Request

4220-06-8 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

4220-06-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4220-06-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,2 and 0 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4220-06:
(6*4)+(5*2)+(4*2)+(3*0)+(2*0)+(1*6)=48
48 % 10 = 8
So 4220-06-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H21NO3.ClH/c1-3-19-14(18)15(8-10-16(2)11-9-15)12-4-6-13(17)7-5-12;/h4-7,17H,3,8-11H2,1-2H3;1H

4220-06-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 4-(4-hydroxyphenyl)-1-methylpiperidine-4-carboxylate

1.2 Other means of identification

Product number -
Other names p-hydroxymeperidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4220-06-8 SDS

4220-06-8Upstream product

4220-06-8Downstream Products

4220-06-8Relevant academic research and scientific papers

TLC identification adn GLC determination of meperidine and its metabolites in biological fluids.

Yeh,Krebs

, p. 482 - 486 (1981)

Procedures were developed for TLC identification and GLC determination of meperidine and its metabolites, i.e., p-hydroxymeperidine, normeperidine, and meperidinic and normeperidinic acids. Meperidine, p-hydroxymeperidine, and normeperidine were extracted with ether from biological fluids at pH 10, whereas meperidinic and normeperidinic acids and conjugated metabolites remained in the aqueous phase. The residue, upon evaporation of the extract to dryness, was derivatized with trifluoroacetic anhydride and gas chromatographed. Total (free and conjugated) meperidinic and normeperidinic acids in the aqueous phase were converted and determined as meperidine and normeperidine, respectively. A preliminary result of urinary disposition of meperidine and its metabolites in the rat is presented. The identity of these metabolites was confirmed with GLC-mass spectrometry.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 4220-06-8