422267-92-3Relevant academic research and scientific papers
1,2-Bond shift of the Fe(CO)3 moiety in the 1,5-O-heterocyclization of (1,3-dienyl)-tricarbonyliron diols: Application to the synthesis of novel phosphocholines
Braun, Alain,Lellouche, Jean-Paul
, p. 329 - 338 (2001)
A novel concept of intramolecular cationic 1,5-O-heterocyclization of ψ-exo-/ψ-endo-(1,3-dienyl)tricarbonyliron diols has been demonstrated to occur under acid catalysis with a quite unusual 1,2-migration of the complexation site. This cationic cyclization has been shown to be stereoselective when involving homochiral precursor diols. It allowed straightforward access to new racemic and optically active conformationally locked alkylphosphocholines as potential anticancer agents.
