422322-71-2

Basic information

• Product Name: carbobenzoxy-L-serylglycine β-tosylate
• Synonyms: carbobenzoxy-L-serylglycine β-tosylate
• CAS NO: 422322-71-2
• Molecular Weight: 450.469
• Mol File: 422322-71-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: carbobenzoxy-L-serylglycine β-tosylate(CAS DataBase Reference)
• NIST Chemistry Reference: carbobenzoxy-L-serylglycine β-tosylate(422322-71-2)
• EPA Substance Registry System: carbobenzoxy-L-serylglycine β-tosylate(422322-71-2)

Safety Data

• Hazardous Substances Data: 422322-71-2(Hazardous Substances Data)

Upstream product

• 30735-20-7 N-benzyloxycarbonylserylglycine 
• 133-59-5 Toluene-2-sulfonyl chloride 

Relevant articles and documents

Inhibitors of transglutaminase

The present invention relates to a chemical compound of the formula (I): in which R1 is: R2 is H, alkyl, which may optionally be substituted by halogen or N2, or NH2; m and o are 0 to 3 and n is 0 or 1; ap, bq and cr are amino acid chains and p, q and r denote the number of amino acids, where a and/or b and/or c may likewise comprise at least one side chain represented by (CH2)mYn(CH2)oC(Z)R2 where Y, Z, R2, m, n, and o have the same meanings as in formula (I), and p, q and r may be identical or different and are an integer from 0 to 1000; R3 and R4 are, independently of one another, H, alkyl, aryl, a heterocycle, an amino protective group or a carboxyl protective group; R5 and R6 are, independently of one another, alkyl which may comprise at least one heteroatom selected from N, O and S, aryl or a heterocycle; X is a methine group, a nitrogen or phosphorus atom; Y is an oxygen atom, sulfur atom or an NH group; and Z is an oxygen atom, sulfur atom or an NR7 group, where R7 is H, alkyl, aryl, a heterocycle, O-alkyl, O-aryl, O-heterocycle, NR2 or NHCONR2, where R is H, alkyl, aryl or a heterocycle, and to the use thereof as inhibitor of transglutaminases.