422556-08-9

Basic information

• Product Name: PYROXSULAM
• Synonyms: PYROXSULAM;Pyroxsulam [iso];N-(5,7-Dimethoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)-3-pyridinesulfonamide;3-Pyridinesulfonamide,N-(5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)-
• CAS NO: 422556-08-9
• Molecular Formula: C₁₄H₁₃F₃N₆O₅S
• Molecular Weight: 434.354
• Mol File: 422556-08-9.mol

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.68
• Refractive Index: 1.633
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 1.92±0.30(Predicted)
• CAS DataBase Reference: PYROXSULAM(CAS DataBase Reference)
• NIST Chemistry Reference: PYROXSULAM(422556-08-9)
• EPA Substance Registry System: PYROXSULAM(422556-08-9)

Safety Data

• Hazardous Substances Data: 422556-08-9(Hazardous Substances Data)

Usage

Uses

Used in Agricultural Industry:
PYROXSULAM is used as a herbicide for controlling a wide range of broadleaf and grassy weeds in various crops. Its application reason is to protect the crops from weed competition, ensuring better growth and yield.
Additionally, PYROXSULAM can be used in combination with other herbicides to provide a more effective and broad-spectrum weed control, reducing the need for multiple applications and minimizing the risk of herbicide resistance development in weeds.

InChI:InChI=1/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)

Upstream product

• 13223-43-3 5,7-dimethoxy-[1,2,4]-triazolo-[1,5-a]-pyrimidin-2-amine 
• 219715-41-0 2-methoxy-4-(trifluoromethyl)-pyridine-3-sulfonyl chloride 

Relevant articles and documents

CRYSTALLINE FORMS OF N-(5,7-DIMETHOXY-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YL)-2-METHOXY-4-(TRIFLUOROMETHYL)PYRIDINE-3-SULFONAMIDE

The present invention relates to novel crystalline forms of N-(5,7-dimethoxy- [1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide (pyroxsulam) A-G, to processes for their preparation, mixtures and compositions comprising them and to the methods of using said crystals and said compositions as pesticidal agents for treating crops and plants.

A dingding sulphur grass amine preparation method (by machine translation)

The invention provides a method for preparing dingding sulphur grass amine, belongs to herbicide preparation technical field. By dingding sulphur grass amine 2 - amino - 5, 7 - dimethoxy [1, 2, 4] triazolo [1, 5 - a] pyrimidine in the organic solvent and 2 - methoxy - 4 - (trifluoromethyl) - pyridine - 3 - sulfonyl chloride in the presence of organic base condensation under the reaction conditions. The condensation reaction is 4 - dimethylamino pyridine carried out under catalysis. The present invention provides a method for preparing dingding sulphur grass amine of higher yield, simple operation, high safety, and is suitable for industrial production. (by machine translation)

Application of the tisler triazolopyrimidine cyclization to the synthesis of a crop protection agent and an intermediate

A new synthetic route to the Dow AgroSciences early stage sulfonamide herbicide 3-(2-methoxy-4-trifluoromethyl)-N-(5,7-dimethoxy[1,2,4]triazolo[1,5-a] pyrimidin-2-yl)pyridinesulfonamide (pyroxsulam) has been developed. The synthesis is based on formation of the triazole ring as the final step, utilizing the Tisler triazolopyrimidine cyclization. A Tisler cyclization route to 2-amino-5,7-dimethoxy-1,2,4-trazolo[1,5-a]pyrimidine starting with 2-chloro-4,6-dimethoxypyrimidine has also been demonstrated.

Process for the preparation of N-([1,2,4]triazolopyrimidin-2-yl)aryl sulfonamides

The N-arylsulfilimine-catalyzed coupling of aromatic sulfonyl chlorides with N-([1,2,4]triazolopyrimidin-2-yl)amines to form N-([1,2,4]triazolo-pyrimidin-2-yl)aryl sulfonamides is improved by the selection of 3-picoline or 3,5-lutidine as the base.