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2-(2-Chloroethyl)pyridine hydrochloride is a chemical compound characterized by a pyridine ring with a chloroethyl group attached to it. It exists as a hydrochloride salt, indicating a positively charged ion paired with a negatively charged chloride ion. 2-(2-Chloroethyl)pyridine hydrochloride is known for its reactivity due to the chloroethyl group, making it a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. However, it is also recognized as a potentially hazardous chemical that requires careful handling to prevent skin and respiratory irritation.

4226-37-3

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4226-37-3 Usage

Uses

Used in Organic Synthesis:
2-(2-Chloroethyl)pyridine hydrochloride is used as a reactive intermediate for the synthesis of various organic compounds. Its chloroethyl group allows for a range of chemical reactions, facilitating the creation of diverse chemical entities.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2-(2-Chloroethyl)pyridine hydrochloride is utilized as a key component in the development of drugs. Its unique structure and reactivity contribute to the formation of medicinally relevant molecules, potentially leading to new treatments and therapies.
Used in Agrochemical Development:
2-(2-Chloroethyl)pyridine hydrochloride is also employed in the agrochemical sector, where it serves as a building block for the synthesis of compounds used in crop protection and pest management. Its role in creating effective and targeted agrochemicals is crucial for enhancing agricultural productivity and sustainability.
Used in Specialty Chemicals Manufacturing:
2-(2-Chloroethyl)pyridine hydrochloride finds application in the production of specialty chemicals, which are tailored for specific industries such as coatings, adhesives, and materials science. The versatility of 2-(2-Chloroethyl)pyridine hydrochloride in synthesis makes it a valuable asset in creating customized chemical solutions for various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 4226-37-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,2 and 6 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4226-37:
(6*4)+(5*2)+(4*2)+(3*6)+(2*3)+(1*7)=73
73 % 10 = 3
So 4226-37-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H8ClN.ClH/c8-5-4-7-3-1-2-6-9-7;/h1-3,6H,4-5H2;1H

4226-37-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2-chloroethyl)pyridine,hydrochloride

1.2 Other means of identification

Product number -
Other names 2-(2-Chlor-aethyl)-pyridin,Hydrochlorid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4226-37-3 SDS

4226-37-3Upstream product

4226-37-3Relevant academic research and scientific papers

PIPERAZINONE-SUBSTITUTED TETRAHYDRO-CARBOLINE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USES THEREOF

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Page/Page column 19, (2012/06/30)

The present invention relates to piperazinone-substituted tetrahydro-carboline derivatives of formula (I): having the substituents as described herein which are melanin-concentrating hormone (MCH-1) receptor antagonists. The present invention also relates

AZINONE-SUBSTITUTED AZEPINO[b]INDOLE AND PYRIDO-PYRROLO-AZEPINE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USE THEREOF

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Page/Page column 82, (2011/01/12)

Novel MCH-1 receptor antagonists are disclosed. These compounds are used in the treatment of various disorders, including obesity, anxiety, depression, non-alcoholic fatty liver disease, and psychiatric disorders. Methods of making these compounds are als

New 1-(heterocyclylalkyl)-4-(propionanilido)-4-piperidinyl methyl ester and methylene methyl ether analgesics

Bagley,Thomas,Rudo,Spencer,Doorley,Ossipov,Jerussi,Benvenga,Spaulding

, p. 827 - 841 (2007/10/02)

A series of new 1-(heterocyclyalkyl)-4-(propionanilido)-4-piperidinyl methyl esters and methylene methyl ethers have been synthesized and pharmacologically evaluated. In the mouse hot-plate test, the majority of compounds exhibited an analgesia (ED50 1 mg/kg) superior to that of morphine. These studies revealed a pharmacological accommodation for many more structurally diverse and far bulkier aromatic ring systems than the corresponding components of the arylethyl groups of the prototypic methyl ester (carfentanil, 2) and methylene methyl ether (sufentanil, 3 and alfentanil, 4) 4-propionanilido analgesics. Compound 9A (methyl 1-[2-(1H-pyrazol-1-yl)-ethyl]-4-[(1-oxopropyl) phenylamino]-4-piperidinecarboxylate), which exhibited appreciable μ-opioid receptor affinity, was a more potent and short-acting analgesic, than alfentanil with less respiratory depression in the rat. On the other hand, the phthalimides 57A and 57B, which exhibited negligible affinity for opioid receptors associated with the mediation of nociceptive transmission (i.e., μ-, κ-, and δ-subtypes), displayed analgesic efficacy in all antinociception tests. In addition, while 57B, compared to clinical opioids, showed a superior recovery of motor coordination after regaining of righting reflex from full anesthetic doses in the rat rotorod test, 57A showed significantly less depression of cardiovascular function at supraanalgesic doses in the isoflurane-anesthetized rat.

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