42287-97-8

Usage

Uses

Used in Pharmaceutical Industry:
3-CYANO-BENZENEPROPANOIC ACID is used as a building block for the synthesis of various biologically active molecules, contributing to the development of new pharmaceuticals. Its unique structure allows for the creation of diverse compounds with potential therapeutic properties.
Used in Organic Chemistry:
3-CYANO-BENZENEPROPANOIC ACID is used as a reagent in organic synthesis, enabling the formation of a wide range of organic compounds. Its versatility in chemical reactions makes it a valuable component in the synthesis of various organic molecules.
Used in Antiviral and Antibacterial Research:
3-CYANO-BENZENEPROPANOIC ACID is used as a subject of study for its potential antiviral and antibacterial properties. Research into its biological activity may lead to the development of new treatments for viral and bacterial infections.
Safety Considerations:
It is important to handle 3-CYANO-BENZENEPROPANOIC ACID with caution, as it may have toxic effects if ingested or inhaled. Proper safety measures should be taken during its use to minimize potential health risks.

InChI:InChI=1/C10H9NO2/c11-7-9-3-1-2-8(6-9)4-5-10(12)13/h1-3,6H,4-5H2,(H,12,13)

Upstream product

• 16642-93-6 (3E)-3-(3-cyanophenyl)acrylic acid 
• 52116-81-1 methyl 3-(3-cyanophenyl) acrylate 
• 24964-64-5 3-Cyanobenzaldehyde 
• 193151-11-0 3-(3-cyano-phenyl)-propionic acid methyl ester 
• 32858-79-0 3-cyanocinnamic acid 

Downstream Products

• 207985-88-4 (S)-3-(3-Cyano-phenyl)-2-hydroxy-propionic acid methyl ester 
• 193151-12-1 3-(3-cyanophenyl)propionic acid thiopyridyl ester 
• 207985-86-2 3-[3-((S)-4-Benzyl-2-oxo-oxazolidin-3-yl)-3-oxo-propyl]-benzonitrile 
• 207985-87-3 3-[(S)-3-((S)-4-Benzyl-2-oxo-oxazolidin-3-yl)-2-hydroxy-3-oxo-propyl]-benzonitrile 
• 83101-13-7 3-(3-cyanophenyl)-1-propanol 
• 83101-15-9 3-(3-bromopropyl)cyanobenzene 
• 1005199-95-0 3-[2-[5-(1H-benzotriazol-5-yl)-1,3,4-oxadiazol-2-yl]ethyl]benzonitrile 
• 193151-11-0 3-(3-cyano-phenyl)-propionic acid methyl ester 
• 202208-74-0 3-(3-Cyano-phenyl)-propionyl chloride 

Relevant academic research and scientific papers

Synthesis and in vitro evaluation of human FP-receptor selective prostaglandin analogues

The in vitro evaluation of a series of saturated prostaglandins revealed that compounds with omega chin aromatic rings retain nanomolar potency for the human prostaglandin F receptor (hFP receptor), exemplified by compound 8. In contrast, the double bonds are required for activity in the series with an acyclic omega chain as in PGF(2α). (C) 2000 Published by Elsevier Science Ltd.

Identification and initial structure-activity relationships of a novel class of nonpeptide inhibitors of blood coagulation factor Xa

The discovery and some of the basic structure-activity relationships of a series of novel nonpeptide inhibitors of blood coagulation Factor Xa is described. These inhibitors are functionalized β-alanines, exemplified by 2a. Docking experiments placing 2a in the active site of Factor Xa implied that the most expeditious route to enhancing in vitro potency was to modify the group occupying the S3 site of the enzyme. Increasing the hydrophobic contacts between the inhibitor and the enzyme in this region led to 8, which has served as the prototype for this series. In addition, an enantioselective synthesis of these substituted β-alanines was also developed.

Organic compounds and their pharmaceutical use

There are provided anti-allergic pharmaceutical compounds of formula: STR1 in which n is 0, 1 or 2; R1 is a hydrocarbyl group containing 6 to 30 carbon atoms and optionally substituted with an optionally substituted phenyl group; R2