42288-29-9

Basic information

• Product Name: 2-((3,5-dichlorophenyl)arnino)acetic acid
• Synonyms: 2-((3,5-dichlorophenyl)arnino)acetic acid
• CAS NO: 42288-29-9
• Molecular Weight: 220.055
• Mol File: 42288-29-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-((3,5-dichlorophenyl)arnino)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((3,5-dichlorophenyl)arnino)acetic acid(42288-29-9)
• EPA Substance Registry System: 2-((3,5-dichlorophenyl)arnino)acetic acid(42288-29-9)

Safety Data

• Hazardous Substances Data: 42288-29-9(Hazardous Substances Data)

Upstream product

• 501008-39-5 ethyl 2-((3,5-dichlorophenyl)amino)acetate 
• 626-43-7 3,5-Dichloroaniline 

Downstream Products

• 1374241-92-5 (R)-2-(3,5-dichlorophenylamino)-1-(3-(methyl(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethanone 
• 1374239-07-2 (R)-2-(3,5-dichlorophenylamino)-1-(3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethanone 
• 1374239-01-6 (S)-1-(3-(1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)piperidin-1-yl)-2-(3,5-dichlorophenylamino)ethanone 
• 1374239-34-5 1-{(S)-3-[(2-aminopyrimidin-4-yl)methylamino]piperidin-1-yl}-2-(3,5-dichlorophenylamino)ethanone 
• 1374242-70-2 2-(3,5-dichlorophenylamino)-1-((S)-3-(methylamino)piperidin-1-yl)ethanone 
• 1374239-27-6 1-((S)-3-(2-aminopyrimidin-4-ylamino)piperidin-1-yl)-2-(3,5-dichlorophenylamino)ethanone 
• 1374242-68-8 2-(3,5-dichlorophenylamino)-1-((S)-3-aminopiperidin-1-yl)ethanone 
• 1374238-87-5 (S)-1-(3-(1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)piperidin-1-yl)-(3,5-dichlorophenylamino)ethanone 
• 1374241-37-8 1-(3-(4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2-((3,5-dichlorophenyl)amino)ethanone 
• 1374240-12-6 1-(3-(6-amino-1H-imidazo[4,5-c]pyridin-1-yl)piperidin-1-yl)-2-((3,5-dichlorophenyl)amino)ethanone 
• 1374243-39-6 2-(3,5-dichlorophenylamino)-1-(6-(methyl(7-tosyl-7H-pyrrolo[2,3-d]pyrirnidin-4-yl)amino)-1,4-oxazepan-4-yl)ethanone 
• 1374242-86-0 2-(3,5-dichlorophenylamino)-1-(3-{methyl-[7-(tosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}azepan-1-yl)ethanone 
• 1374242-83-7 2-(3,5-dichlorophenylamino)-1-(3-(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)azepan-1-yl)ethanone 
• 1374239-47-0 1-(3-(1H-pyrazolo[3,4-d]pyrimidin-4-yl-N-methylamino)azepan-1-yl)-2-(3,5-dichlorophenylamino)ethanone 

Relevant articles and documents

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Disclosed herein are certain acetamido derivatives that are DNA Polymerase Theta (Polθ) inhibitors of Formula (I). Also, disclosed are pharmaceutical compositions comprising such compounds and methods of treating diseases treatable by inhibition of Polθ such as cancer, including homologous recombination (HR) deficient cancers.