423-50-7 Usage
General Description
Perfluorohexane sulfonyl fluoride (PFHSF) is a volatile fluorosulfuryl compound used in producing fluorochemical derivatives and surfactants. This chemical often pops up as a versatile fluorinating agent or as an intermediate in the synthesis of fluorinated molecules used in industrial applications because of its stability, resistance to degradation, and low reactivity. However, the same properties that make it suitable for industrial use also make it highly persistent and bioaccumulative in the environment, raising concerns about its potential impacts on human health and the environment. PFHSF poses adverse human health risks associated with long-term exposure, including endocrine disruption, cancer, and potential developmental and reproductive toxicity. It has also been detected in the environment, including water systems and wildlife, indicating its extensive distribution and persistence.
Check Digit Verification of cas no
The CAS Registry Mumber 423-50-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,2 and 3 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 423-50:
(5*4)+(4*2)+(3*3)+(2*5)+(1*0)=47
47 % 10 = 7
So 423-50-7 is a valid CAS Registry Number.
InChI:InChI=1/C6F14O2S/c7-1(8,3(11,12)5(15,16)17)2(9,10)4(13,14)6(18,19)23(20,21)22
423-50-7Relevant articles and documents
An entirely new methodology for synthesizing perfluorinated compounds: Synthesis of perfluoroalkanesulfonyl fluorides from non-fluorinated compounds
Okazoe, Takashi,Murotani, Eisuke,Watanabe, Kunio,Itoh, Masahiro,Shirakawa, Daisuke,Kawahara, Kengo,Kaneko, Isamu,Tatematsu, Shin
, p. 1695 - 1701 (2007/10/03)
A new synthetic procedure for the preparation of perfluoroalkanesulfonyl fluorides utilizing liquid-phase direct fluorination with elemental fluorine has been developed. Direct fluorination of a partially fluorinated ester, which has alkanesulfonyl fluoride in the end, was synthesized from non-fluorinated counterparts and perfluorinated acid fluoride according to the PERFECT process, gave the desired perfluorinated product in moderate yield as well as by-products arising from CS bond cleavage. The results of the direct fluorination of some model substrates suggest that the CS bond cleavage occurred due to radical formation at the α-position rather than the β-position.
