4231-43-0

Upstream product

• 621-95-4 4,4'-diaminodihydrostilbene 
• 90-02-8 salicylaldehyde 
• 736-30-1 1,2-bis(4-nitrophenyl)ethane 
• 89-95-2 2-methyl-benzyl alcohol 

Relevant academic research and scientific papers

Synthetic, structural and biological properties of binuclear complexes with some Schiff bases

The complexes of Co(II), Ni(II) and Cu(II) with N,N′-bis-[5-X- salicylidene]-4,4′-diaminodibenzyl, abbreviated as H2-XSalPDADB (X = -H, -CH3, -Br) have been synthesized and investigated by elemental analysis, electrical conductance, magnetic, spectral and thermal studies. The molar conductivity data indicate that the complexes are non-electrolytes. Analytical data support 1:1 (M:L) stoichiometry. The reflectance spectra along with the magnetic data suggest pseudo-tetrahedral geometry for the complexes. The Schiff bases function as tetradentate ligands coordinating through ON-NO donor system. Substitution in the phenyl ring of the complexes produces shift in the azomethine ν(C=N) stretching vibrational frequency, which is related to the Hammett's substituent perameter (σ). The 1H-NMR data reveal that all Schiff bases exist in enol-iminic form. Various ESR parameters for copper complexes have been calculated. The compounds have been screened for their biological activities.

Synthesis and Fungicidal Activity of Novel 4,4′-Bis(2″ -aryl-5″-methyl/unsubstituted-4″-oxo-thiazolidin-3″-yl) Bibenzyl

Reduction followed by nitration of benzil I yielded 4,4′- dinitrobibenzyl (III) which by reduction furnished quantitatively and analytically pure 4,4′-diaminobibenzyl (IV) which on condensation with different carbonyl compounds gave 4,4′-bis (benzylideneamino) bibenzyls (Va-f). Compounds (Va-f) on cycloaddition with mercaptoacetic acid/2-mercaptopropionic acid yielded the corresponding 4-oxothiazolidin-3-yl bibenzyls (Vla-I). The compounds VIg-I have two chiral centers in each thiazolidinone moiety so two diastereomers are possible, but on crystallization and repeated chromatography, one diastereomer was obtained. The absolute configuration of the diastereomer was tentatively assigned on the basis of 1H NMR spectra. 1H NMR spectra of the product showed a distinct doublet at δ 1.22 for C5-CH3 of thiazolidinone ring (22, 23) and a distinct quartet at δ4.20 for the C5-H proton. Similarly, the C2 proton showed an independent singlet at δ 5.95, so the diastereomers obtained were assigned trans configuration. Compounds Va-f and Vla-I were evaluated in vitro for their fungitoxicities against Fusarium oxysporium and Penicillium citrinum. All the compounds were found to be antifungal active. Some of the compounds displayed activities comparable with that of the commercial fungicide Dithane M-45. Structure-activity relationships for the screened compounds are discussed.

AZOMETHINE METAL-COMPLEXED PIGMENTS FROM THE BIBENZYL SERIES

A new series of Schiff bases derived from 4,4'-diamino- and 2,2'-diaminobibenzyl have been prepared and characterized.UV, IR and NMR spectra suggest that the ligands 7 and 8 formed by salicylaldehyde only exist in the enoliminic form, while the ligands 9