42310-02-1

Basic information

• Product Name: 5-fluorohistidine
• Synonyms: 5-Fluorohistidine; histidine, 5-fluoro-
• CAS NO: 42310-02-1
• Molecular Formula: C₆H₈FN₃O₂
• Molecular Weight: 173.145
• Mol File: 42310-02-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 454.8°C at 760 mmHg
• Flash Point: 228.9°C
• Density: 1.529g/cm³
• Vapor Pressure: 4.61E-09mmHg at 25°C
• Refractive Index: 1.586
• CAS DataBase Reference: 5-fluorohistidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-fluorohistidine(42310-02-1)
• EPA Substance Registry System: 5-fluorohistidine(42310-02-1)

Safety Data

• Hazardous Substances Data: 42310-02-1(Hazardous Substances Data)

Upstream product

• 1033248-05-3 3-(5-fluoro-1H-imidazol-4-yl)-2-(2,2,2-trifluoro-acetylamino)-propionic acid methyl ester 

Relevant articles and documents

An enantioselective synthesis of (S)-4-fluorohistidine

We report a new synthesis of enantiomerically pure (S)-4-fluorohisitidine based on diastereoselective alkylation of MOM-protected 4-fluoro-5-bromomethyl imidazole using the Sch?llkopf bis-lactim amino acid synthesis. Improvements in procedures for preparation of key intermediates are also described. (S)-4-Fluorohisitidine prepared by this new method was identical in all respects to material prepared by previous procedures.