42313-51-9Relevant academic research and scientific papers
Multivalent thioglycopeptoids via photoclick chemistry: Potent affinities towards LecA and BC2L-A lectins
Caumes,Gillon,Legeret,Taillefumier,Imberty,Faure
supporting information, p. 12301 - 12304 (2015/07/27)
Solution-phase synthesis of linear and cyclic β- and α,β-peptoids was coupled to photo-induced thiol-ene coupling reaction to readily access multivalent thioglycoclusters. A tetrameric cyclic β-peptoid scaffold displaying 1-thio-β-D-galactose or 1-thio-α-D-mannose has revealed by ITC experiments efficient binding potency for bacterial lectins LecA and BC2L-A, respectively.
Equimolar CO2 capture by N-substituted amino acid salts and subsequent conversion
Liu, An-Hua,Ma, Ran,Song, Chan,Yang, Zhen-Zhen,Yu, Ao,Cai, Yu,He, Liang-Nian,Zhao, Ya-Nan,Yu, Bing,Song, Qing-Wen
supporting information, p. 11306 - 11310 (2013/01/15)
Steric bulk controls CO2 absorption: N-substituted amino acid salts in poly(ethylene glycol) reversibly absorb CO2 in nearly 1:1 stoichiometry. Carbamic acid is thought to be the absorbed form of CO 2; this was supported by NMR and in situ IR spectroscopy, and DFT calculations. The captured CO2 could be converted directly into oxazolidinones and thus CO2 desorption could be sidestepped. Copyright
Complex containing a Lewis acid and Bronsted acid for the catalytic reactions of aza-Michael addition
Mao, Xin-Xin,Wang, Jiao,Xia, Qun-Hua,Shen, Yong-Miao
experimental part, p. 525 - 528 (2011/10/31)
The novel efficient complex catalyst containing a Lewis acid and a Bronsted acid have been prepared by the reaction of proline ion liquid and cuprous iodide. The catalyst was characterized by FT-IR techniques using pyridine as probe molecule. A fast, mild, and quantitative procedure for aza-Michael addition reactions between various amines and α,β- unsaturated carbonyl compounds and nitriles has been developed using the novel complex catalyst. The results showed that the novel catalyst owned high activities for the reactions with excellent yields within 1 min.
Sterically controlled stereoregulation in aldol reactions of 3-aryl-1-alkyl dihydrothiouracils
Kumar, Varun,Khatik, Gopal L.,Nair, Vipin A.
scheme or table, p. 2997 - 3001 (2012/01/13)
Aldol reactions of 3-aryl-1-alkyl dihydrothiouracils were investigated with respect to the orientation of the exocyclic group at N1, electronic effects of the aryl substituent at N3 and the steric demands of the electrophile. The reactions highlight the preference for formation of the anti aldol diastereomer with increasing steric constraints of the reactants. Georg Thieme Verlag Stuttgart · New York.
Novel efficient procedure for the conjugate addition of amines to electron deficient alkenes
Sun, Xudong,Du, Yijun,Li, Chunqing,Qi, Chenze
experimental part, p. 653 - 656 (2011/02/16)
The novel efficient procedure has been developed for the conjugate addition of amines to electron deficient alkenes using the novel SO3H functionalized ionic liquid as catalyst. The results showed that the novel catalyst owned high activities for the reactions with excellent yields within several minutes. Various amines and electron deficient alkenes were successfully transformed to the corresponding products in the catalytic system. Operational simplicity, without need of any solvent, low cost of the catalyst used, room temperature, high yields, reusability, excellent chemoselectivity and wide applicability are the key features of this methodology.
The Use of 3-Alkyl-2,4-Diketopiperidines in Asymmetric Michael Additions
Ambroise, Lydia,Chassagnard, Claude,Revial, Gilbert,d'Angelo, Jean
, p. 407 - 410 (2007/10/02)
Chiral enamine 12, derived from 2,4-diketopiperidine 11 added to methyl acrylate, leading, after hydrolytic work-up to adduct 15 (94percent stereoselectivity).
Tetrahydroisoquinoline compounds and a pharmaceutical composition thereof
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, (2008/06/13)
A tetrahydroisoquinoline compound of the formula: STR1 wherein R1 is alkyl of one to six carbon atoms, cycloalkyl of three to six carbon atoms, allyl or propargyl, R2 is hydrogen or alkyl of one to six carbon atoms, and R3 is hydrogen, alkyl of one to six carbon atoms or benzyl. Methods for preparing the compound (I) are disclosed. The compound (I) and a pharmaceutically acceptable salt thereof are useful as a diagnostic or therapeutic agent for angiotensin-related hypertension.
