423157-45-3

Upstream product

• 128726-47-6 (+)-(S)-6-hydroxymethyl-2-piperidinone 
• 97347-42-7 (+)-(S)-N₂,N₆-bis[(1,1-dimethylethoxy)carbonyl]-6-oxo-lysine methyl ester 
• 2483-48-9 (+)-(S)-N₂,N₆-bis[(1,1-dimethylethoxy)carbonyl]-lysine methyl ester 
• 158414-69-8 (-)-(S)-6-oxo-2-piperidinecarboxylic acid methyl ester 

Downstream Products

• 423157-51-1 (3R,8aS)-3-(4-Methoxy-phenyl)-tetrahydro-oxazolo[3,4-a]pyridin-5-one 
• 423157-46-4 (-)-(6S)-(4-methoxybenzyloxymethyl)-1-(4-nitrobenzoyl)-2-piperidinone 
• 423157-47-5 (8aS,3R)-3-(4-methoxyphenyl)-1,5,8,8a-tetrahydro[1,3]oxazolo[3,4-a]pyridin-5-one 
• 423157-48-6 6-(4-methoxy-benzyloxymethyl)-5,6-dihydro-1H-pyridin-2-one 
• 423157-49-7 (-)-(6S)-(4-methoxybenzyloxymethyl)-2-oxo-1,2,3,6-tetrahydro-1-pyridinyl-4-nitrophenylmethanone 

Relevant academic research and scientific papers

Diels-Alder reactions of 6-substituted 1-(p-nitrobenzoyl)-5,6-dihydro-2-pyridinones

The first examples of Diels-Alder cycloaddition reactions of 6-substituted 1-(p-nitrobenzoyl)-5,6-dihydro-2-pyridinones are described. This reaction benefits from the fact that the diene adopts an endo orientation trans to the axial substituent at C-6 due to A1,3 allylic type strain with the N-PNB protecting group.