4236-49-1 Usage
Purine derivative
A compound based on the purine ring structure, which is a heterocyclic aromatic organic compound.
Purine ring structure
A double-ring structure consisting of a 6-membered pyrimidine ring fused to a 5-membered imidazole ring.
Amine group at the 6th position
A functional group with a nitrogen atom bonded to two organic groups, located at the 6th position of the purine ring.
N,N-bis(phenylmethyl) groups
Two groups consisting of a phenyl ring (a 6-membered carbon ring with delocalized electrons) connected to a methyl group (a carbon atom with three hydrogen atoms) through an amino group (-NH2).
Potential applications in medicinal chemistry and drug development
Purine derivatives have been studied for their various biological activities, including as potential anti-cancer, anti-inflammatory, and antiviral agents.
Specific pharmacological properties
The presence of the N,N-bis(phenylmethyl) groups may impart specific pharmacological properties to the compound.
Enhanced binding affinity to biological targets
The presence of the N,N-bis(phenylmethyl) groups may enhance the compound's binding affinity to biological targets, potentially improving its efficacy as a drug.
Further research needed
Further studies are needed to fully understand the potential uses and properties of 1H-Purin-6-amine, N,N-bis(phenylmethyl)-.
Check Digit Verification of cas no
The CAS Registry Mumber 4236-49-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,3 and 6 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4236-49:
(6*4)+(5*2)+(4*3)+(3*6)+(2*4)+(1*9)=81
81 % 10 = 1
So 4236-49-1 is a valid CAS Registry Number.
4236-49-1Relevant academic research and scientific papers
2-n-butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization
Minetti, Patrizia,Tinti, Maria Ornella,Carminati, Paolo,Castorina, Massimo,Di Cesare, Maria Assunta,Di Serio, Stefano,Gallo, Grazia,Ghirardi, Orlando,Giorgi, Fabrizio,Giorgi, Luca,Piersanti, Giovanni,Bartoccini, Francesca,Tarzia, Giorgio
, p. 6887 - 6896 (2007/10/03)
Two types of adenosine receptor ligands were designed, i.e., 9H-purine and 1H-imidazo[4,5-c]pyridines, to obtain selective A2A antagonists, and we report here their synthesis and binding affinities for the four adenosine receptor subtypes Asub
