42365-62-8 Usage
Uses
Used in Pharmaceutical Industry:
3,5-Bis(trifluoromethyl)benzylamine is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and properties make it a valuable component in the development of new drugs and medications.
Used in Agrochemical Industry:
In the agrochemical industry, 3,5-bis(trifluoromethyl)benzylamine serves as a key intermediate in the production of various agrochemicals, including pesticides and herbicides. Its incorporation into these products enhances their effectiveness in controlling pests and weeds, thereby contributing to increased crop yields and agricultural productivity.
Safety and Disposal:
Due to its potential health hazards and environmental impact, handling 3,5-bis(trifluoromethyl)benzylamine requires careful precautions to prevent skin, eye, and respiratory tract irritation. Proper disposal of 3,5-BIS(TRIFLUOROMETHYL)BENZYLAMINE should be carried out in strict accordance with local regulations to minimize its adverse effects on the environment and human health.
Check Digit Verification of cas no
The CAS Registry Mumber 42365-62-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,3,6 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 42365-62:
(7*4)+(6*2)+(5*3)+(4*6)+(3*5)+(2*6)+(1*2)=108
108 % 10 = 8
So 42365-62-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H7F6N.ClH/c10-8(11,12)6-1-5(4-16)2-7(3-6)9(13,14)15;/h1-3H,4,16H2;1H
42365-62-8Relevant academic research and scientific papers
Soloshonok, Vadim A.,Yasumoto, Manabu
, p. 889 - 893 (2006)
This paper describes an efficient, practical synthesis of 3,5-bis(trifluoromethyl)benzylamine via biomimetic transamination of 3,5-bis(trifluoromethyl)benzaldehyde with benzylamine. From a synthetic standpoint the reported procedure is highly operationall
Hydrosilylative reduction of primary amides to primary amines catalyzed by a terminal [Ni-OH] complex
Bera, Jitendra K.,Pandey, Pragati
, p. 9204 - 9207 (2021/09/20)
A terminal [Ni-OH] complex1, supported by triflamide-functionalized NHC ligands, catalyzes the hydrosilylative reduction of a range of primary amides into primary amines in good to excellent yields under base-free conditions with key functional group tolerance. Catalyst1is also effective for the reduction of a variety of tertiary and secondary amides. In contrast to literature reports, the reactivity of1towards amide reduction follows an inverse trend,i.e., 1° amide > 3° amide > 2° amide. The reaction does not follow a usual dehydration pathway.
