423719-54-4

Basic information

• Product Name: FMOC-THZ-OH
• Synonyms: FMOC-THIOPRO-OH;FMOC-THZ-OH;FMOC-(R)-THIAZOLIDINE-4-CARBOXYLIC ACID;FMOC-L-THZ-OH;(-)-FMOC-L-THIAPROLINE;FMOC-L-THIAPROLINE;FMOC-L-THIAZOLIDINE-4-CARBOXYLIC ACID;FMOC-L-THIOPROLINE
• CAS NO: 423719-54-4
• Molecular Formula: C₁₉H₁₇NO₄S
• Molecular Weight: 355.41
• Mol File: 423719-54-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: 153-158 °C
• Boiling Point: 591.614 °C at 760 mmHg
• Flash Point: 311.597 °C
• Appearance: /
• Density: 1.402 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.668
• Storage Temp.: 2-8°C
• PKA: 3.47±0.20(Predicted)
• CAS DataBase Reference: FMOC-THZ-OH(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-THZ-OH(423719-54-4)
• EPA Substance Registry System: FMOC-THZ-OH(423719-54-4)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 423719-54-4(Hazardous Substances Data)

Usage

General Description

Fmoc-thz-OH is a synthetic organic compound widely used in peptide synthesis and drug development. It is derived from the amino acid threonine and consists of an N-terminal Fmoc (fluorenylmethyloxycarbonyl) protecting group, followed by the thiazolidine carboxylic acid moiety. Fmoc-thz-OH is a key building block for the construction of thiazolidine-containing peptides, which have shown potential as antimicrobial and anticancer agents. Its unique structure and functional groups make it a valuable tool for the modification and creation of biologically active peptides, making it of interest to researchers and pharmaceutical companies.

InChI:InChI=1/C19H17NO4S/c21-18(22)17-10-25-11-20(17)19(23)24-9-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16-17H,9-11H2,(H,21,22)/t17-/m1/s1