423755-08-2

Upstream product

• 1975-52-6 5-nitro-o-toluic acid 
• 1004-00-8 4-chloro-2-aminobenzenethiol 
• 690243-08-4 5-chloro-2-(2-methyl-5-nitro-phenyl)-benzothiazole 

Relevant academic research and scientific papers

Synthesis and SAR of 2-arylbenzoxazoles, benzothiazoles and benzimidazoles as inhibitors of lysophosphatidic acid acyltransferase-β

2-Arylbenzoxazoles, benzothiazoles and benzimidazoles were identified as new classes of potent, isoform specific inhibitors of lysophosphatidic acid acyltransferase-β (LPAAT-β). Effects of selected inhibitors on proliferation of tumor cells in vitro were investigated.

Benzoxazole LPAAT-B inhibitors and uses thereof

The invention relates to benzoxazoles and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said benzoxazoles. The invention also relates to methods for screening for LPAAT-β activity.