423757-27-1

Basic information

• Product Name: 3,5-difluorophenylacetyl-Gly-Pro-OH
• Synonyms: 3,5-difluorophenylacetyl-Gly-Pro-OH
• CAS NO: 423757-27-1
• Molecular Weight: 326.3
• Mol File: 423757-27-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,5-difluorophenylacetyl-Gly-Pro-OH(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-difluorophenylacetyl-Gly-Pro-OH(423757-27-1)
• EPA Substance Registry System: 3,5-difluorophenylacetyl-Gly-Pro-OH(423757-27-1)

Safety Data

• Hazardous Substances Data: 423757-27-1(Hazardous Substances Data)

Upstream product

• 29022-11-5 N-(fluoren-9-ylmethoxycarbonyl)glycine 
• 105184-38-1 3,5-difluorophenyl acetic acid 

Relevant articles and documents

FAP-activated anti-tumor compounds

The invention relates to a prodrug that is capable of being converted into a drug by the catalytic action of human fibroblast activation protein (FAPα), said prodrug is chemically stable under physiological conditions and can be used for the manufacture of physically stable aqueous formulations. It has a cleavage site which is recognised by FAPα, and the drug released by the enzymatic activity of FAPα is cytotoxic or cytostatic under physiological conditions.