423768-46-1 Usage
General Description
Methyl 5-(chlorosulfonyl)-4-methyl-2-thiophenecarboxylate is a chemical compound with the molecular formula C10H9ClO4S2. It is a white to off-white solid with a molecular weight of 291.76 g/mol. METHYL 5-(CHLOROSULFONYL)-4-METHYL-2-THIOPHENECARBOXYLATE is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also utilized in the production of dyes and pigments, as well as in the research and development of new chemical compounds. Methyl 5-(chlorosulfonyl)-4-methyl-2-thiophenecarboxylate is considered to be a versatile building block for various organic chemical reactions, making it an important compound in the field of organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 423768-46-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,3,7,6 and 8 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 423768-46:
(8*4)+(7*2)+(6*3)+(5*7)+(4*6)+(3*8)+(2*4)+(1*6)=161
161 % 10 = 1
So 423768-46-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H7ClO4S2/c1-4-3-5(6(9)12-2)13-7(4)14(8,10)11/h3H,1-2H3
423768-46-1Relevant articles and documents
Pyrimidine derivatives, and preparation method and use thereof
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Paragraph 0108; 0109; 0110; 0111; 0112, (2016/10/08)
Pyrimidine derivatives disclosed in the invention respectively contain an aromatic five-membered heterocycle, a lone electron pair on a hetero atom S, O or N and an unsaturated five-membered ring form a conjugated system, and the lone electron pair effect of above hetero atoms has an inhibition effect on vascular endothelial growth factor (VEGF) receptors VEGFR-1, VEGFR-2 and VEGFR-3, so the pyrimidine derivatives are very good kinase inhibitors. The pyrimidine derivatives have stronger VEGFR-1, VEGFR-2 and VEGFR-3 inhibition activity than pazopanib in the prior art, and can be used treat VEGF signal pathway inhibition diseases, such as lung cancer, kidney cell cancer and other solid tumors.
C:Corrosive;
