42389-57-1

Basic information

• Product Name: 3-AMINO-1-METHYL-PIPERIDINE 2 HCL
• Synonyms: 3-AMINO-1-METHYL-PIPERIDINE 2 HCL;3-AMINO-1-METHYLPIPERIDINE DIHYDROCHLORIDE;3-AMINO-1-METHYL-PIPERIDINE X 2 HCL >98%;3-AMINO-1-METHYL-PIPERIDINEX2HCL;3-Amino-1-methyl-piperidine;1-methylpiperidin-3-amine(SALTDATA: FREE);1-Methyl-3-piperidinamine;1-Methyl-3-aMinopiperidine dihydrochloride
• CAS NO: 42389-57-1
• Molecular Formula: C₆H₁₄N₂
• Molecular Weight: 187.11
• Mol File: 42389-57-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 230-240°C
• Boiling Point: 136℃
• Flash Point: 37℃
• Appearance: /
• Density: 0.912
• Vapor Pressure: 7.36mmHg at 25°C
• Refractive Index: 1.469
• PKA: 10.40±0.20(Predicted)
• CAS DataBase Reference: 3-AMINO-1-METHYL-PIPERIDINE 2 HCL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-1-METHYL-PIPERIDINE 2 HCL(42389-57-1)
• EPA Substance Registry System: 3-AMINO-1-METHYL-PIPERIDINE 2 HCL(42389-57-1)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-41-37/38-22
• Safety Statements: 26-36/37/39-39
• HazardClass: IRRITANT
• Hazardous Substances Data: 42389-57-1(Hazardous Substances Data)

Usage

Uses

3-Amino-1-methylpiperidine dihydrochloride (cas# 894808-73-2) is used as a reagent in the preparation of phenylindoles as tryptophan 2,3-dioxygenase inhibitors.

InChI:InChI=1/C6H14N2/c1-8-4-2-3-6(7)5-8/h6H,2-5,7H2,1H3

Upstream product

• 42389-58-2 3-Amino-1-methyl-pyridinium-bromid 

Downstream Products

• 1254049-66-5 6-ethyl-5-[(1-methylpiperidin-3-yl)amino]-3-{[3-(methylsulfonyl)phenyl]amino}pyrazine-2-carboxamide 
• 1226788-07-3 C₁₄H₁₇ClFN₃O₂ 
• 1260242-85-0 C₂₇H₂₉F₆N₇ 
• 1304355-35-8 C₁₂H₁₇N₃O₂ 

Relevant articles and documents

Synergistine derivatives having anti-bacterial activity and their use

The invention provides new synergistine derivatives of the formula: STR1 in which Y=H or N(CH3)2 and (a) R1 and R2 =H and R=pyrrolidin-3-ylthio or piperidin-3-ylthio or piperidin-4-ylthio (optionally substituted by alkyl), or altenatively R=alkylthio substituted by 1 or 2 SO3 H radicals or alkylamino or dialkylamino radicals (optionally substituted) or by 1 or 2 piperazino rings (optionally substituted) or morpholino, thiomorpholino, piperidino, pyrrolidin-1-yl, piperidin-2-yl, piperidin-3-yl or piperidin-4-yl or pyrrolidin-2-yl or pyrrolidin-3-yl rings (these last 5 rings being optionally substituted by alkyl), or (b) R1 and R2 form a bond and R=pyrrolidin-3-ylamino, piperidin-3-ylamino or piperidin-4-ylamino, pyrrolidin-3-yloxy, piperidin-3-yloxy or piperidin-4-yloxy, pyrrolidin-3-ylthio, piperidin-3-ylthio or piperidin-4-ylthio (optionally substituted by alkyl), or alternatively R=alkylamino, alkoxy or alkylthio substituted by 1 or 2 SO3 H radicals, alkylamino or dialkylamino radicals (optionally substituted) or trialkylammonio or imidazol-4-yl or imidazol-5-yl radicals or by 1 or 2 piperazino rings (optionally substituted by alkyl) or morpholino, thiomorpholino, piperidino, pyrrolidin-1-yl, piperidin-2-yl, piperidin-3-yl or piperidin-4-yl or pyrrolidin-2-yl or pyrrolidin-3-yl rings (these last two rings being optionally substituted by alkyl), and their salts, their preparation, and the pharmaceutical compositions in which they are present. These compounds are useful as anitbacterial agents.