42399-79-1

Upstream product

• 35053-55-5 N'-(6-chloropyridazin-3-yl)-N,N-dimethylmethanimidamide 
• 51519-15-4 3-(hydroxyiminomethyleneamino)-6-chloropyridazine 

Downstream Products

• 132846-38-9 8-Benzyl-6-chloro-9-phenyl-8H-pyrazolo<4,3-d>-s-triazolo<1,5-b>pyridazine 
• 132846-37-8 7-Benzyl-6-chloro-9-phenyl-7H-pyrazolo<4,3-d>-s-triazolo<1,5-b>pyridazine 
• 132846-48-1 6-Chloro-9-methyl-9-phenyl-9H-pyrazolo<4,3-d>-s-triazolo<1,5-b>pyridazine 
• 132846-44-7 6-Chloro-9-methyl-9-phenyl-7,8-dihydro-9H-pyrazolo<4,3-d>-s-triazolo<1,5-b>pyridazine 
• 152537-81-0 6-(3-sulfamoyl-1-propylthio)[1,2,4]triazolo[1,5-b]pyridazine 
• 152537-14-9 6-(2,2-dimethyl-3-sulfamoyl-1-propoxy)[1,2,4]triazolo[1,5-b]pyridazine 
• 152537-56-9 6-(2,2-diethyl-3-sulfamoyl-1-propoxy)[1,2,4]triazolo[1,5-b]pyridazine 
• 152537-79-6 6-[3-(N,N-dimethylsulfamoyl)-1-propoxy][1,2,4]triazolo[1,5-b]pyridazine 
• 152537-80-9 6-[3-(1-methyl-4-piperazinylsulfonyl)-1-propoxy][1,2,4]triazolo[1,5-b]pyridazine 
• 1375801-31-2 benzylcyclopentyl[1.2.4]triazolo[1,5-b]pyridazin-6-ylamine 

Relevant academic research and scientific papers

HERBICIDAL COMPOUNDS

Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as a pesticides, especially as herbicides.

Synthetic studies on condensed-azole derivatives. V. Synthesis and anti- asthmatic activities of ω-sulfamoylalkyloxy[1,2,4]triazolo[1,s-b]pyridazines

A series of novel ([1,2,4]triazolo[1,5-b]pyridazin-6- yl)oxyalkylsulfonamides was synthesized and evaluated for the ability to inhibit platelet activating factor (PAF)-induced bronchoconstriction in guinea pigs. The compounds bearing a gem-dialkyl or a cycloalkylidene group at the 2 position of the sulfamoylpropyloxy group in the side chain and a methyl group at the 7 position were found to have potent activity. Among them, 2,2-diethyl-3-(7-methyl[l,2,4]-triazolo[1,5-b]pyridazin-6- yl)oxypropanesulfonamide (13) showed excellent anti-asthmatic activity. Compouds 13 may be of significant value in the treatment of asthma and other respiratory diseases. The structure-activity relationships in this series of compounds are discussed.