42406-52-0Relevant articles and documents
SYNTHESIS OF OPTICALLY ACTIVE N2-PHTHALOYLASPARTIMIDE.
TOHYAMA,ONDA
, p. 372 - 373 (1964)
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42406-52-0
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Basic information
- Product Name: N-ALPHA-PHTHALYL-L-ASPARAGINE
- Synonyms: 2-(1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-SUCCINAMIC ACID;PHT-ASN-OH;PHTHALYL-L-ASPARAGINE;PHTHALOYL-L-ASPARAGINE;N-ALPHA-PHTHALYL-L-ASPARAGINE;(S)-2-(1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-SUCCINAMIC ACID;N-α-Phthaloyl-L-asparagine;N-a-Phthaloyl-L-asparagine
- CAS NO:42406-52-0
- Molecular Formula: C12H10N2O5
- Molecular Weight: 262.22
- EINECS: N/A
- Product Categories: N/A
- Mol File: 42406-52-0.mol
- Article Data: 1
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 576.135 °C at 760 mmHg
- Flash Point: 302.236 °C
- Appearance: /
- Density: 1.574 g/cm3
- Vapor Pressure: 4.09E-14mmHg at 25°C
- Refractive Index: 1.656
- Storage Temp.: Store at 0°C
- Solubility: N/A
- CAS DataBase Reference: N-ALPHA-PHTHALYL-L-ASPARAGINE(CAS DataBase Reference)
- NIST Chemistry Reference: N-ALPHA-PHTHALYL-L-ASPARAGINE(42406-52-0)
- EPA Substance Registry System: N-ALPHA-PHTHALYL-L-ASPARAGINE(42406-52-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 42406-52-0(Hazardous Substances Data)
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42406-52-0 Usage
Description
N-Alpha-Phthalyl-L-asparagine is a chemical compound that functions as a peptide coupling reagent in peptide synthesis. It acts as a protecting group for the amino group of asparagine, thereby preventing unwanted side reactions during the synthesis process. Known for its high efficiency and selectivity in peptide bond formation, it is a valuable tool in peptide chemistry.Uses
Used in Pharmaceutical Industry:N-Alpha-Phthalyl-L-asparagine is used as a peptide coupling reagent for the production of peptide-based drugs. It facilitates the synthesis process by protecting the amino group of asparagine, ensuring the formation of the desired peptide bonds with high efficiency and selectivity.
Used in Biochemical Research:
In biochemical research, N-Alpha-Phthalyl-L-asparagine is used as a peptide coupling reagent for the synthesis of custom peptides. Its protective role for the amino group of asparagine allows for the creation of specific peptide sequences with precision, contributing to the advancement of peptide-based research and development.
It is important to handle N-Alpha-Phthalyl-L-asparagine with care due to potential health risks if not properly managed, emphasizing the need for safety precautions in its application.
Check Digit Verification of cas no
The CAS Registry Mumber 42406-52-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,4,0 and 6 respectively; the second part has 2 digits, 5 and 2 respectively.Calculate Digit Verification of CAS Registry Number 42406-52:
(7*4)+(6*2)+(5*4)+(4*0)+(3*6)+(2*5)+(1*2)=90
90 % 10 = 0
So 42406-52-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H10N2O5/c13-9(15)5-8(12(18)19)14-10(16)6-3-1-2-4-7(6)11(14)17/h1-4,8H,5H2,(H2,13,15)(H,18,19)/t8-/m0/s1
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N-ALPHA-PHTHALYL-L-ASPARAGINE
