42416-20-6

Usage

Uses

Used in Pharmaceutical Industry:
2-(pyridin-2-ylthio)ethanamine(SALTDATA: 2HCl) is used as a pharmaceutical intermediate for the development of drugs targeting central nervous system disorders. Its unique chemical structure allows it to interact with specific receptors and pathways in the nervous system, potentially leading to the treatment of various neurological conditions.
Used in Organic Synthesis:
2-(pyridin-2-ylthio)ethanamine(SALTDATA: 2HCl) serves as a key building block in the synthesis of various organic compounds. Its versatile structure can be modified and functionalized to create a wide range of molecules with different properties and applications.
Used in Antiviral Research:
2-(pyridin-2-ylthio)ethanamine(SALTDATA: 2HCl) is used as a potential antiviral agent in research settings. Its ability to interact with viral proteins and enzymes may help inhibit viral replication and reduce the severity of viral infections.
Used in Research and Laboratory Settings:
The dihydrochloride salt form of 2-(pyridin-2-ylthio)ethanamine is commonly used in research and laboratory settings for the study of its chemical properties, reactivity, and potential applications in various fields, including drug discovery and development.

Upstream product

• 151-56-4 ethyleneimine 
• 2637-34-5 2-Sulfanylpyridine 
• 870-24-6 2-chloroethanamine hydrochloride 
• 107-09-5 2-bromoethylamine 
• 109-04-6 2-bromo-pyridine 
• 156-57-0 2-mercaptoethylamine hydrochloride 
• 155965-47-2 2-[2'-(pyridin-2''-sulfanyl)ethyl]-1H-isoindole-1,3(2H)-dione 
• 689-98-5 chloroethylamine 
• 109-09-1 2-chloropyridine 

Downstream Products

• 106669-45-8 N-Benzoyl-N'-[3-(1H-imidazol-4-yl)-propyl]-N''-[2-(pyridin-2-ylsulfanyl)-ethyl]-guanidine 
• 1257527-86-8 RRRQRRCcystCcystRGY 

Relevant academic research and scientific papers

Antibacterial and catecholase activities of Co(III) and Ni(II) Schiff base complexes

X-ray structural analyses of two newly synthesized Schiff base-complexes, [Co(L)3] (1) and [Ni(L)2] (2) [HL = 2-((E)-(2-pyridine-2-pyridin-2-ylthio)ethylimino)methyl)phenol], reveal the bidentate chelation behavior of the ligand HL w

Synthesis of N-heterocyclic ligands for use in affinity and mixed mode chromatography

A set of heterocyclic ligands have been synthesised for use in the preparation of mixed mode affinity chromatographic adsorbents for application in the purification of proteins, including antibodies. The ligand structures were designed to consist of a pyridinyl or related aza-heterocyclic nucleus bearing a pendant arm containing either an alkylamine, alkylthiol or hydroxyalkyl nucleophilic group to allow their facile immobilisation onto an activated support matrix. Ligand diversity was achieved by altering the length of the alkyl chain between the heterocyclic nucleus and nucleophilic group, varying the position of alkyl chain attachment to the heterocycle, and incorporating extra substituents into the pyridinyl or related aza-heterocyclic ring. This diversity in ligand structure was intended to enable key structural features of the ligand, required for efficient protein binding, to be determined. In contrast to the previously used multi-step procedures for the preparation of analogous substituted pyridine or aza-heterocyclic compounds, the synthesis routes for the ligands described here have generally utilized very mild, one-step reactions with readily available heterocyclic precursors. Copyright

Pyrazole Compound

The present invention provides a pyrazole compound represented by the formula (I): wherein ring A0 is a pyrazole ring optionally further having 1 or 2 substituents; Ra is a substituted carbamoyl group; and Rb is an optionally substituted acylamino group, or a salt thereof or a prodrug thereof, which is useful as an agent for the prophylaxis or treatment of GSK-3β related pathology or disease, and a GSK-3β inhibitor including same.

INDANE DERIVATES AS MUSCARINIC RECEPTOR AGONISTS

The present invention relates to compounds of Formula I: I which are agonists of the M-1 muscarinic receptor.

2-PROPENE-1-ONES AS HSP 70 INDUCERS

The present invention relates to novel compounds of 2-propene-1-one series, of general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them, wherein R5, R6, Q and Y are as defined in the specification. The present invention also relates to a process for preparing such compounds, compositions containing such compounds, and use of such compound and composition in medicine. The compounds of the general formula (I) induce HSP-70 and are useful for the treatment of diseases accompanying pathological stress in a living mammalian organism, including a human being, such as stroke, myocardial infarction, inflammatory disorder, hepatotoxicity, sepsis, diseases of viral origin, allograft rejection, tumourous diseases, gastric mucosal damage, brain haemorrhage, endothelial dysfunctions, diabetic complications, neuro-degenerative diseases, post-traumatic neuronal damage, acute renal failure, glaucoma and aging related skin degeneration.

MUSCARINIC AGONISTS

The present invention relates to compounds of Formula (I): which are agonists of the M-1 muscarinic receptor.

Binuclear Platinum(II) Complexes bridged by Pyridine-2-thiolate and Related Ligands. Synthesis and Crystal Structure

Bis(ethylenediamine)di-μ-pyridine-2-thiolato-diplatinum(II) chloride trihydrate (1), bis(ethylenediamine)di-μ-4-methylpyridine-2-thiolato-diplatinum(II) chloride dihydrate (2), and di(μ-2-aminoethyl 2-pyridyl sulphide)-bis chloride trihydrate (3) were synthesized and their structures investigated by means of X-ray crystallography.The binuclear complexes (1) and (2) have the head-to-head configuration in which planar PtN2S2 and PtN4 co-ordination spheres face one another with Pt...Pt distances of 3.083(1) Angstroem in (1) and 3.101(1) Angstroem in (2).The two co-ordination spheres are slanted against one another and twisted about the Pt...Pt axis, the interplanar and the torsion angles being 31.0(3) and 32.6(3) deg in (1) and 31.9(2) and 34.3(2) deg in (2).In complex (3) two planar PtN2SCl co-ordination spheres bridged by two pyridine-2-thiol segments have an eclipsed conformation; the interplanar and torsion angles are much less than those of (1) and (2).The complex is of the head-to-tail isomer and has an approximate two-fold axis perpendicular to the Pt...Pt axis.The Pt...Pt distance is 2.956(1) Angstroem.Both of the head-to-head dimers in (1) and (2) form a centrosymmetric pair of the dimers in the solid state, the PtN2S2 co-ordination planes of the respective dimers being in contact with one another.The intermedier Pt...Pt distance is 3.613(1) Angstroem in (1) and 3.726(2) Angstroem in (2).