42436-56-6 Usage
Description
1,2-Dilauroyl-sn-Glycero-3-PhosphatidylethanolaMine, also known as DLPE, is a synthetic phospholipid derivative belonging to the family of phosphatidylethanolamines. It consists of two lauric acid chains attached to a glycerol backbone, with an ethanolamine head group. Due to its structural similarity to natural phospholipids found in cell membranes, DLPE is widely used in biomedical research as a model membrane lipid. It also plays a role in the development of liposomal drug delivery systems and lipid bilayer systems for studying membrane protein function. Furthermore, DLPE has been investigated for its potential involvement in cell signaling, membrane fusion, and other biological processes.
Uses
Used in Biomedical Research:
1,2-Dilauroyl-sn-Glycero-3-PhosphatidylethanolaMine is used as a model membrane lipid for [studying the structure and function of cell membranes and their components].
Used in Drug Delivery Systems:
1,2-Dilauroyl-sn-Glycero-3-PhosphatidylethanolaMine is used as a component in liposomal drug delivery systems for [enhancing the solubility, stability, and targeted delivery of therapeutic agents].
Used in Lipid Bilayer Systems:
1,2-Dilauroyl-sn-Glycero-3-PhosphatidylethanolaMine is used in lipid bilayer systems for [investigating the function and interactions of membrane proteins].
Used in Cell Signaling and Membrane Fusion Research:
1,2-Dilauroyl-sn-Glycero-3-PhosphatidylethanolaMine is used as a research tool for [exploring its potential role in cell signaling pathways and membrane fusion processes].
Check Digit Verification of cas no
The CAS Registry Mumber 42436-56-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,4,3 and 6 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 42436-56:
(7*4)+(6*2)+(5*4)+(4*3)+(3*6)+(2*5)+(1*6)=106
106 % 10 = 6
So 42436-56-6 is a valid CAS Registry Number.
42436-56-6Relevant articles and documents
A diacyl phosphatidyl ethanolamine preparation method (by machine translation)
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Paragraph 0093; 0094; 0095, (2018/11/22)
The invention provides a diacyl phosphatidyl ethanolamine preparation method, comprises the following steps: (1) solvent and organic/inorganic alkali under the action of, the formula I compound and phosphorus reagent undergo the substitution reaction, formula a intermediate 1; (2) in the same reaction system, intermediate 1 of an organic/inorganic the presence of an alkali, with 2 - (N - [...] carbonyl amino) ethanol or N - Boc protection of the ethanolamine undergo the substitution reaction, formula b intermediate 2; (3) in the same reaction system, intermediate 2 under the action of the oxidizing agent in the oxidation reaction, the compound of formula II; (4) the formula II compound in the solvent, under the action of alkali, phospholipid base hydrolysis, formula III compound. The advantage of this invention is characterized in that: the invention only needs two-step synthesis of the target product can be obtained, and the method is easy to control conditions, after treatment is simple, less side reaction, high yield, consistent with the requirements of industrial production. (by machine translation)