4244-40-0

Upstream product

• 107-13-1 acrylonitrile 
• 87-42-3 6-chloropurine 
• 2417-90-5 bromopropionitrile 

Downstream Products

• 827584-80-5 3-{6-[(Z)-Benzyloxyimino]-1,6-dihydro-purin-9-yl}-propionitrile 
• 827585-22-8 3-{6-[(Z)-3,4-Dimethoxy-benzyloxyimino]-1,6-dihydro-purin-9-yl}-propionitrile 
• 827585-06-8 7-(5-adamantan-1-yl-3-methyl-pent-2-enyl)-1,7-dihydro-purin-6-one O-(3,4-dimethoxy-benzyl)-oxime 
• 827585-36-4 7-(3-methyl-but-2-enyl)-1,7-dihydro-purin-6-one O-(3,4-dimethoxy-benzyl)-oxime 
• 827585-45-5 7,8,9,10-tetrahydro-10-(3,4-dimethoxybenzyloxy)-9,9-dimethyl[1,4]diazepino[1,2,3-g,h]purine 
• 827584-86-1 7,8,9,10-tetrahydro-10-(benzyloxy)-8-iodo-9,9-dimethyl[1,4]diazepino[1,2,3-g,h]purine 
• 827584-84-9 7-(3-methyl-but-2-enyl)-1,7-dihydro-purin-6-one O-benzyl-oxime 
• 827584-88-3 7,8,9,10-tetrahydro-10-(benzyloxy)-9,9-dimethyl[1,4]diazepino[1,2,3-g,h]purine 
• 827584-71-4 7,8,9,10-tetrahydro-10-hydroxy-9,9-dimethyl[1,4]diazepino[1,2,3-g,h]purine 

Relevant academic research and scientific papers

Regioselective N9 alkylation of purine rings assisted by β-cyclodextrin

Under the assistance of β-cyclodextrin, purine was effectively alkylated at N9 together with up to 99% conversion and good to excellent yield using water as the solvent. High regioselectivity-N9/N7 selectivity>99:1 was attributed to the β-cyclodextrin cav

Preparation of derivatives of 1-(2-pyrimidinyl)piperazine as potential antianxiety, antidepressant, and antipsychotic agents

(Chemical Equation Presented) This paper describes the preparation of twenty-eight derivatives of 1-(2-pyrimidinyl)piperazine as potential antianxiety, antidepressant, and antipsychotic agents. In twenty-six of the preparations a chloro nitrogen heterocycle was caused to react with an excess of 1-(2-pyrimidinyl)piperazine in the absence of solvent. A specific example is given above.

Microwave-promoted Michael addition in neat water: A rapid, efficient and green method for the preparation of acyclic nucleosides

Syntheses of acyclic nucleosides were achieved in water with the aid of microwave irradiation, providing a rapid, efficient and convenient method for the preparation of acyclic nucleosides in high yields. Georg Thieme Verlag Stuttgart.

Synthesis of 9-substituted tetrahydrodiazepinopurines: Studies toward the total synthesis of asmarines

(Chemical Equation Presented). A methodology for the preparation of asmarine analogues has been developed. The asmarines are cytotoxic marine alkaloids with a unique tetrahydro[1,4]diazepino[1,2,3-g,h]purine (THDAP) structure. Three cyclization methods we