42453-19-0 Usage
Uses
Used in Pharmaceutical Industry:
IFOSFAMIDE IMPURITY E is used as a reference material for monitoring and controlling its levels in ifosfamide formulations. This is crucial to ensure the safety and efficacy of pharmaceutical products containing ifosfamide for the treatment of cancer and other medical conditions.
IFOSFAMIDE IMPURITY E is used as a quality control parameter for assessing the purity and safety of ifosfamide-based pharmaceutical products. By closely monitoring its presence, manufacturers can minimize the risk of genotoxic, mutagenic, and carcinogenic effects associated with this impurity.
IFOSFAMIDE IMPURITY E is also used in research and development for the improvement of manufacturing processes and the development of alternative antineoplastic agents with reduced impurity levels, thereby enhancing the overall safety and effectiveness of cancer treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 42453-19-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,4,5 and 3 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 42453-19:
(7*4)+(6*2)+(5*4)+(4*5)+(3*3)+(2*1)+(1*9)=100
100 % 10 = 0
So 42453-19-0 is a valid CAS Registry Number.
42453-19-0Relevant academic research and scientific papers
Synthesis and antitumor activity of two ifosfamide analogs with a five-membered ring
Kutscher,Niemeyer,Engel,Kleemann,Hilgard,Pohl,Scheffler
, p. 323 - 326 (2007/10/02)
Two ifosfamide (CAS 3778-73-2) analogs with a five-membered ring, i.e. the oxazaphospholidine derivatives 6 and 7, were synthesized and their cytotoxic activity in vitro, acute toxicity and antitumor activity in vivo determined in comparison with the oxaz
