42463-67-2Relevant academic research and scientific papers
β'β ANIONIC ELIMINATION OF CARBOXYLIC ESTERS
Aubert, Corinne,Begue, Jean-Pierre,Biellmann, Jean-Francois
, p. 5581 - 5590 (2007/10/02)
The elimination of lithium, magnesium and aluminium enolates of isobutyrates of medium ring cyclanols occurs in a syn fashion.A set of experimental procedures is presented.This elimination seems to be restricted to strained systems.The stereochemistry has been determined on stereospecifically deuterated cyclooctanol isobutyrates.The primary isotope effect kH/k2 was 3.0 +/- 0.1 and the secondary 1.1.The name β'β elimination is proposed for this syn elimination and related elimination.
