42469-23-8Relevant academic research and scientific papers
Formation of N,O-acetalsin the production of x-ray contrast agents
Haland, Torfinn,Sydnes, Leiv K.
, p. 1181 - 1190 (2014/12/10)
Acetylation of 1 with acetic anhydride, an important step in the preparation of iohexol, gave the corresponding acetanilide and minor amounts of a few byproducts, whose structures have been elucidated. Among the byproducts were some 1,3-oxazolidines which survived when the reaction was quenched by adding methanol and water under strong acidic conditions.
Aminolysis of N-acyllactams
Stehlicek, Jaroslav,Sebenda, Jan
, p. 2524 - 2531 (2007/10/02)
The overall second-order rate constants of aminolysis of N-benzoyllactams of different ring size, the rate constants of aminolysis of N,N'-isophthaloyl- and N,N'-terephthaloylbis(6-hexanelactam) to the first and second stages and the ratio of splitting of the exocyclic and endocyclic amide bond by octylamine were determined in THF at 50 deg C.The effect of the type of amine and medium on the rate of aminolysis was examined.
