424839-30-5Relevant academic research and scientific papers
Efficient asymmetric synthesis of α-alkylated benzylic methyl sulfonates
Enders, Dieter,Vignola, Nicola,Berner, Otto M.,Harnying, Wacharee
, p. 3231 - 3243 (2007/10/03)
The first highly efficient auxiliary-controlled synthesis of various α-substituted sulfonic acid derivatives is described. Alkyl or aryl halides were reacted with lithiated benzylic sulfonic esters bearing 1,2:5,6-di-O-isopropylidene-α-d-allofuranose as a
The first highly efficient asymmetric synthesis of α-substituted methyl sulfonates
Enders, Dieter,Vignola, Nicola,Berner, Otto M.,Bats, Jan W.
, p. 109 - 111 (2007/10/03)
The right choice of sugar auxiliary led to a breakthrough in the first asymmetric α-alkylations of sulfonic acid esters (see scheme). The high asymmetric inductions were reached with 1,2:5,6-di-O-isopropyliden-α-D-allofuranose as the auxiliary group, whic
