42491-77-0

Basic information

• Product Name: 4-BENZYLOXYCARBONYLAMINO-2-HYDROXY-BUTYRIC ACID
• Synonyms: Butanoicacid, 2-hydroxy-4-[[(phenylmethoxy)carbonyl]amino]-, (R)- (9CI);(R)-4-(Benzyloxycarbonylamino)-2-hydroxybutyric acid;(R)-4-[(Benzyloxycarbonyl)amino]-2-hydroxybutanoic acid
• CAS NO: 42491-77-0
• Molecular Formula: C₁₂H₁₅NO₅
• Molecular Weight: 253.25
• Mol File: 42491-77-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 521.2±50.0 °C(Predicted)
• Appearance: /
• Density: 1.311±0.06 g/cm3(Predicted)
• PKA: 3.73±0.10(Predicted)
• CAS DataBase Reference: 4-BENZYLOXYCARBONYLAMINO-2-HYDROXY-BUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BENZYLOXYCARBONYLAMINO-2-HYDROXY-BUTYRIC ACID(42491-77-0)
• EPA Substance Registry System: 4-BENZYLOXYCARBONYLAMINO-2-HYDROXY-BUTYRIC ACID(42491-77-0)

Safety Data

• Hazardous Substances Data: 42491-77-0(Hazardous Substances Data)

Upstream product

• 81323-56-0 Methyl N-benzyloxycarbonyl-4-amino-2-oxobutanoate 
• 54755-69-0 L-(-)-4-benzyloxycarbonylamino-2-hydroxybutyric acid 

Downstream Products

• 31771-40-1 (R)-β-hydroxy-4-aminobutyric acid 
• 959919-11-0 (R)-2-benzyloxy-4-benzyloxycarbonylaminobutyric acid 

Relevant articles and documents

Enantioselective Syntheses of (S)- and (R)-3-Hydroxypyrrolidin-2-ones via Lactate Dehydrogenase Catalysed Reductions of 4-Benzyloxycarbonylamino-2-oxobutanoic Acid

The first examples of the BS- and SE-lactate dehydrogenase catalysed reductions of an α-keto acid incorporating a nitrogen containing function in the side chain are described: (S)- and (R)-benzyloxycarbonylamino-2-hydroxybutanoic acids were prepared in good yield and excellent enantioselectivities and were converted to the (S)- and (R)-3-hydroxypyrrolidin-2-ones respectively.

The preparation and biological activity of novel amino acid analogs of butirosin.

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