42499-46-7Relevant academic research and scientific papers
Facile formation of N-alkyl-oxazolidin-2-ones from N-alkyl- nitroxyethylamines and carbonate anion in biphasic media
Sitzmann, Michael E.,Kenar, James A.,Trivedi, Nirupam J.
, p. 8211 - 8212 (2007/10/03)
Nitration of N-alkyl ethanolamines (1) followed by treatment of their corresponding N-alkyl-N-(2-nitroxyethyl)amine salts (2) in a biphasic CH2Cl2/aqueous Na2CO3 or NaHCO3 mixture at 25°C gives N-alkyl- oxazolidin-2-ones (3). This represents a new method that allows the preparation of oxazolidinones at ambient temperature with the use of aqueous carbonate.
