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(5-chlorothiophen-2-yl)acetonitrile is a chemical compound characterized by its molecular formula C8H6ClNS. It is a nitrile derivative of 5-chlorothiophene, a heterocyclic compound that contains both a sulfur and a chlorine atom. (5-chlorothiophen-2-yl)acetonitrile features an acetonitrile group, which renders it a versatile intermediate for the synthesis of a wide range of organic compounds, such as pharmaceuticals, agrochemicals, and other fine chemicals. Due to the presence of nitriles, it is essential to handle (5-chlorothiophen-2-yl)acetonitrile with care, as they can be toxic and cause irritation to the skin, eyes, and respiratory system.

42520-90-1

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42520-90-1 Usage

Uses

Used in Pharmaceutical Industry:
(5-chlorothiophen-2-yl)acetonitrile is used as a synthetic intermediate for the development of various pharmaceuticals. Its unique structure allows for the creation of complex molecules that can target specific biological pathways, potentially leading to the discovery of new drugs with improved efficacy and reduced side effects.
Used in Agrochemical Industry:
In the agrochemical sector, (5-chlorothiophen-2-yl)acetonitrile is utilized as a building block for the synthesis of novel compounds with pesticidal, herbicidal, or fungicidal properties. Its incorporation into these compounds can enhance their effectiveness in protecting crops from pests and diseases, thereby contributing to increased agricultural productivity.
Used in Organic Chemistry Research:
(5-chlorothiophen-2-yl)acetonitrile serves as a valuable starting material for researchers in organic chemistry. Its reactivity and structural diversity make it an attractive candidate for the preparation of complex organic molecules, which can be used in various applications, including the development of new materials, catalysts, and chemical sensors.
Used in Fine Chemicals Production:
(5-chlorothiophen-2-yl)acetonitrile is also used as an intermediate in the production of fine chemicals, which are high-purity chemicals used in various industries, such as fragrances, dyes, and specialty chemicals. The versatility of (5-chlorothiophen-2-yl)acetonitrile allows for the synthesis of a wide array of fine chemicals with specific properties and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 42520-90-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,5,2 and 0 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 42520-90:
(7*4)+(6*2)+(5*5)+(4*2)+(3*0)+(2*9)+(1*0)=91
91 % 10 = 1
So 42520-90-1 is a valid CAS Registry Number.

42520-90-1Relevant academic research and scientific papers

5-HETEROARYL-3,9-DIAZASPIRO[5.5]UNDECANE COMPOUNDS

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Page/Page column 147, (2020/03/29)

The present invention covers 5-heteroaryl-3,9-diazaspiro[5.5]undecane compounds of general formula (I), in which Y, Z, R1, R2, R3 and R4 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment and/or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.

Cascade iodination-fluorination synthesis of 2-fluorothiophene and 5-fluoro-2-thienyliodonium salts

Onys'ko, Petro P.,Kim, Tetyana V.,Kiseleva, Olena I.,Rassukana, Yuliya V.,Gakh, Andrei A.

experimental part, p. 501 - 504 (2010/01/14)

The first synthesis of fluorine-containing 2-thienyliodonium salts was accomplished using cascade iodination-fluorination. According to this methodology, thiophene is first converted to bis(2-thienyl)iodonium hexafluorophosphate using an electrophilic iodination reaction. Upon heating with potassium fluoride, this salt undergoes regioselective fluorination producing 2-fluorothiophene. 2-Fluorothiophene is then iodinated again to yield fluorothienyliodonium salts.

Novel thiophene derivatives and their preparation

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, (2008/06/13)

Thiophene derivatives of the formula STR1 IN WHICH Rx is --S--CHR5 --CONHOH or --S--CHR5 -5-tetrazolyl in which R5 is H or alkyl of 1-6 carbon atoms and Ry is 0-2 of alkyl or alkoxy of 1-6 carbon atoms or halogen, and their pharmacologically acceptable salts with bases, possess antilipolytic activity.

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