42523-09-1

Basic information

• Product Name: 1,2-Dimethoxy-9H-fluoren-9-one
• Synonyms: 1,2-Dimethoxy-9H-fluoren-9-one
• CAS NO: 42523-09-1
• Molecular Formula: C15H12O3
• Molecular Weight: 240.25
• Mol File: 42523-09-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 419.4±38.0 °C(Predicted)
• Appearance: /
• Density: 1.245±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1,2-Dimethoxy-9H-fluoren-9-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Dimethoxy-9H-fluoren-9-one(42523-09-1)
• EPA Substance Registry System: 1,2-Dimethoxy-9H-fluoren-9-one(42523-09-1)

Safety Data

• Hazardous Substances Data: 42523-09-1(Hazardous Substances Data)

Upstream product

• 67-66-3 chloroform 
• 63723-85-3 1,2-dimethoxybiphenylene 
• 213479-70-0 3',4'-Dimethoxy-biphenyl-2-carboxylic acid diethylamide 
• 88-67-5 2-Iodobenzoic acid 
• 1794-58-7 3',4'-dimethoxy-[1,1'-biphenyl]-2-carboxylic acid 
• 122775-35-3 3,4-Dimethoxyphenylboronic acid 
• 42523-06-8 1-chloro-2-iodo-4,5-dimethoxy-benzene 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 76041-86-6 2-bromo-N,N-diethylbenzamide 
• 2859-78-1 4-Bromoveratrole 
• 42523-08-0 1,2-Dimethoxy-9H-fluorene 
• 91-16-7 1,2-dimethoxybenzene 
• 6311-23-5 2-(toluene-4-sulfonylamino)-benzoic acid 
• 42523-05-7 2'-Chloro-4',5'-dimethoxy-biphenyl-2-carboxylic acid 

Relevant articles and documents

Tricyclic polyhydroxylic tyrosine kinase inhibitors

Certain tricyclic polyhydroxylic compounds, and their pharmaceutically-acceptable salts, are inhibitors of tyrosine kinase enzymes, and so are useful for the control of tyrosine kinase dependent diseases (e.g., cancer, atherosclerosis).

Reaction of 1,2-Dimethoxybiphenylene with Dichlorocarbene. Chemical Detection of the Bond Fixation in Biphenylene Derivatives

1,2-Dimethoxybiphenylene reacted with dichlorocarbene to give three chloro(methoxy)-6H-benzo-cyclobutacyclohepten-6-one derivatives, two chloro(methoxy)fluorenones and two dimethoxyfluorenones.The reaction with dibromocarbene gave similar products.The formation of these products serves an unequivocal chemical evidence for bond fixation of 1,2-dimethoxybiphenylene.The chloro(methoxy)-6H-benzocyclobutacyclohepten-6-one was led to 9-chloro-5-hydroxy-6H-benzocyclobutacyclohepten-6-one, the first tropolone analogue of biphenylene.This compound was shown to exist in only one of the two possible tautomers in contrast with general monocyclic tropolones.