42537-58-6

Usage

InChI:InChI=1/C10H8N2O5/c13-9(5-6-10(14)15)11-7-3-1-2-4-8(7)12(16)17/h1-6H,(H,11,13)(H,14,15)/b6-5+

Upstream product

• 108-31-6 maleic anhydride 
• 88-74-4 2-nitro-aniline 

Downstream Products

• 54012-37-2 2-(3-anilino-4-oxo-2-thioxo-thiazolidin-5-yl)-N-(2-nitro-phenyl)-acetamide 
• 54012-43-0 2-[3-(4-methyl-anilino)-4-oxo-2-thioxo-thiazolidin-5-yl]-N-(2-nitro-phenyl)-acetamide 
• 85142-40-1 (Z)-3-(2-Nitro-phenylcarbamoyl)-acrylic acid ethyl ester 
• 61832-98-2 2-nitrofumaranilic acid 
• 138376-04-2 5-(2-nitro-phenylimino)-5H-furan-2-one 
• 2973-15-1 N-(2-nitrophenyl)maleimide 
• 37931-42-3 ethyl 1,2,3,4-tetrahydro-2-oxo-3-quinoxaline 
• 85142-45-6 ethyl 2-nitrofumaranilate 

Relevant academic research and scientific papers

The synthesis of (Z)-4-oxo-4-(arylamino)but-2-enoic acids derivatives and determination of their inhibition properties against human carbonic anhydrase I and II isoenzymes

The synthesis of (Z)-4-oxo-4-(arylamino)but-2-enoic acid (4) derivatives containing structural characteristics that can be used for the synthesis of several active molecules, is presented. Some of the butenoic acid derivatives (4a, 4c, 4e, 4i, 4j, 4k) are

Curcumin-inspired cytotoxic 3,5-bis(arylmethylene)-1-(N-(ortho-substituted aryl)maleamoyl)-4-piperidones: A novel group of topoisomerase II alpha inhibitors

Three series of novel 3,5-bis(arylmethylene)-1-(N-(ortho-substituted aryl)maleamoyl)-4-piperidones, designed as simplified analogs of curcumin with maleic diamide tether, were synthesized and bioevaluated. These compounds displayed potent cytotoxicity tow

Amorphous carbon-silica composites bearing sulfonic acid as solid acid catalysts for the chemoselective protection of aldehydes as 1,1-diacetates and for N-, O- and S-acylations

Amorphous carbon-silica composites bearing sulfonic acid derived from inexpensive natural organic compounds (glucose, maltose, cellulose, chitosan and starch) were prepared by partial carbonization followed by sulfonation and their catalytic activity was evaluated for the protection of aldehydes as 1,1-diacetates and for N-, O- and S-acylations under solvent-free conditions. Different biomaterials have been chosen, with a view to select the most active solid acid catalyst. Carbon-silica composites were characterized by FTIR, XRD and elemental analysis. Sulfonated carbon-silica composite derived from starch was found to be the most active and could be recycled for several runs without loss of significant activity. It was also characterized by TGA, SEM and TEM.

Preparation, polymerization and characterization of some new maleimides

This article described the synthesis of poly N-arylmaleimides and copolymaleimides. The maleimides monomer N- (2-nitrophenyl)maleimide (2-NPMI), N-(3-nitrophenyl)maleimide (3-NPMI) and N-(4-nitrophenyl)maleimide (4-NPMI) were prepared from corresponding s

Reactions of Cyclic Anhydrides: Part VII - Reductive Cyclisation of 2-Nitromaleanilates and 2-Nitrofumaranilates, a New Synthesis of 2-Oxo-1,2,3,4-tetrahydroquinoxalines

Fusion of o-nitroanilines with maleic anhydride (MA) in the presence of anhydrous aluminum chloride at 80-100 deg selectively furnishes the corresponding maleanilic acids (2a-d) and at 160-200 deg, the fumaranilic acids (4a-d) in excellent yields.Their me

Reactions of Cyclic Anhydrides: Part VI - Transesterification of Maleanilic and Fumaranilic Acids with Phosphorus Pentoxide-Alkanol

Mixed phosphorus esters obtained from alkanols and phosphorus pentoxide furnish the corresponding esters in 80-90percent yield when refluxed with maleanilic and fumaranilic acids.