4254-59-5

Basic information

• Product Name: butanedioic acid, 2-butyl-, (2R)-
• Synonyms: (2R)-2-Butylsuccinic acid
• CAS NO: 4254-59-5
• Molecular Formula: C₈H₁₄O₄
• Molecular Weight: 174.1944
• Mol File: 4254-59-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 281.299°C at 760 mmHg
• Flash Point: 138.166°C
• Density: 1.16g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.474
• CAS DataBase Reference: butanedioic acid, 2-butyl-, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: butanedioic acid, 2-butyl-, (2R)-(4254-59-5)
• EPA Substance Registry System: butanedioic acid, 2-butyl-, (2R)-(4254-59-5)

Safety Data

• Hazardous Substances Data: 4254-59-5(Hazardous Substances Data)

Upstream product

• 10479-26-2 1,2-Biphenylhexane 
• 132631-27-7 (E)-butylidenesuccinic acid 
• 33156-91-1 R-(-)-Dictyopterene C' 

Relevant articles and documents

Diastereoselective conjugate addition of Grignard reagents to a homochiral fumaramide derived from Oppolzer's sultam

Conjugate addition of Grignard reagents to N,N′-fumaroylbis[(2R)- bornane-10,2-sultam] 1 occurred with moderate to high levels of diastereoselectivity. Diastereomeric excesses were estimated by analysis of the 1H NMR spectra of the succinamide mixtures and enantiomeric excesses from 19F NMR spectra of the bis Mosher esters of the diols produced by reductive cleavage of the succinamides. Saponification of the succinamides gave the corresponding (R)-succinic acids with ees up to 92% showing that addition of the Grignard reagents takes place selectively on the re-face of 1.

Asymmetric Synthesis of (R)- and (S)-4-(Substituted Benzyl)dihydrofuran-2(3H)-ones: An Application of the Ruthenium-binap Complex-catalysed Asymmetric Hydrogenation of Alkylidenesuccinic Acids

A concise synthesis of (S)- or (R)-4-(substituted benzyl)dihydrofuran-2(3H)-ones (1) with high enantiomeric purity is presented. (S)- or (R)-(Substituted benzyl)succinic acids (6) 97percent enantiomeric excess) were first prepared by Ru2Cl4(R)- or (S