425633-78-9Relevant academic research and scientific papers
Stereoselective synthesis of 3-alkyl-2-aryltetrahydrofuran-4-ols: Total synthesis of (±)-paulownin
Angle, Steven R.,Choi, Inchang,Tham, Fook S.
, p. 6268 - 6278 (2008/12/22)
(Chemical Equation Presented) A formal [3 + 2]-cycloaddition involving the Lewis acid mediated reaction of α-silyloxy aldehydes and styrenes to afford 3-alkyl-2-aryltetrahydrofuran-4-ols has been developed. This methodology was applied to the total synthesis of the naturally occurring furofuran lignan (±)-paulownin.
