Cas 425635-00-3,2H-Thiopyrano[4,3-d]pyrimidine-1(5H)-propanamide, N-[2-(4-bromophenyl)-2-oxoethyl]-3,4,7,8-tetrahydro-2,4-dioxo-

425635-00-3

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Basic information

Product Name: 2H-Thiopyrano[4,3-d]pyrimidine-1(5H)-propanamide, N-[2-(4-bromophenyl)-2-oxoethyl]-3,4,7,8-tetrahydro-2,4-dioxo-
Synonyms:
CAS NO:425635-00-3
Molecular Formula: C18H18BrN3O4S
Molecular Weight: 452.329
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 2H-Thiopyrano[4,3-d]pyrimidine-1(5H)-propanamide, N-[2-(4-bromophenyl)-2-oxoethyl]-3,4,7,8-tetrahydro-2,4-dioxo-(CAS DataBase Reference)
NIST Chemistry Reference: 2H-Thiopyrano[4,3-d]pyrimidine-1(5H)-propanamide, N-[2-(4-bromophenyl)-2-oxoethyl]-3,4,7,8-tetrahydro-2,4-dioxo-(425635-00-3)
EPA Substance Registry System: 2H-Thiopyrano[4,3-d]pyrimidine-1(5H)-propanamide, N-[2-(4-bromophenyl)-2-oxoethyl]-3,4,7,8-tetrahydro-2,4-dioxo-(425635-00-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 425635-00-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 425635-00-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,5,6,3 and 5 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 425635-00:
(8*4)+(7*2)+(6*5)+(5*6)+(4*3)+(3*5)+(2*0)+(1*0)=133
133 % 10 = 3
So 425635-00-3 is a valid CAS Registry Number.

425635-00-3Upstream product

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425635-00-3Relevant academic research and scientific papers

Substituted uracil derivatives as potent inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)

Steinhagen, Henning,Gerisch, Michael,Mittendorf, Joachim,Schlemmer, Karl-Heinz,Albrecht, Barbara

, p. 3187 - 3190 (2002)

A new class of PARP-1 inhibitors, namely substituted fused uracil derivatives were synthesised. Starting from a derivative with an IC50=2 μM the chemical optimisation program led to compounds with more than a 100-fold increase in potency (ICsu

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