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Usage

Uses

Used in Agricultural Applications:
2,2,2-Trichloro-N-(2-methylphenyl)acetamide is used as a herbicide for controlling the growth of various types of weeds and unwanted plants. It works by inhibiting the enzyme acetolactate synthase, which is crucial for the synthesis of branched-chain amino acids in plants, thereby preventing their growth.
Used in Industrial Applications:
2,2,2-Trichloro-N-(2-methylphenyl)acetamide is used as a herbicide in industrial settings to manage the growth of unwanted plants and weeds, ensuring the maintenance of clean and orderly industrial areas.
Safety Precautions:
It is important to handle 2,2,2-Trichloro-N-(2-methylphenyl)acetamide with caution due to its toxicity to aquatic organisms and potential to cause skin and eye irritation in humans. Safety guidelines and regulations must be followed when using 2,2,2-Trichloro-N-(2-methylphenyl)acetamide to minimize risks and ensure the safety of both the environment and individuals.

Upstream product

• 95-53-4 o-toluidine 
• 76-02-8 trifluoroacetyl chloride 
• 515-84-4 Ethyl trichloroacetate 
• 76-03-9 trichloroacetic acid 
• 116-16-5 1,1,1,3,3,3-hexachloro-propan-2-one 

Downstream Products

• 113260-70-1 N-(o-tolylcarbamoyl)benzamide 
• 1081272-48-1 N-(2-methylphenyl)-N'-(6-methylbenzothiazol-2-yl)urea 
• 1018186-39-4 N-(2-methylphenyl)-N'-(6-chlorobenzothiazol-2-yl)urea 
• 1430847-70-3 14-O-{1-[(2-methylphenyl)ureido]-2-methylpropan-2-ylthioacetyl}mutilin 
• 7477-94-3 2-methyl-4,6-dinitroaniline 

Relevant academic research and scientific papers

Synthesis and antibacterial activities of pleuromutilin derivatives containing aryl urea groups

A series of novel pleuromutilin derivatives containing aryl urea groups was synthesized and their antibacterial activities were evaluated in vitro against S. aureus ATCC 26113, S.aureus SC, S. albus ATCC 8799 and P. aeruginosa ATCC 27853. Most of compound

The Application of N-Substituted Trichloroacetamides as in situ Isocyanate Generating Reagents for the Synthesis of Acylureas and Sulfonylureas

In dimethylsulfoxide solution in the presence of excess of powdered sodium hydroxide, N-substituted trichloroacetamides 1 are used as in situ isocyanate generating reagents which can react with carboxamides or sulfonamides 2 to afford acylureas or sulfonylureas 3.

Formation of N-Substituted Trichloroacetamides from Amines and Hexachloroacetone

Procedures are described for converting primary amines into their well-crystalline trichloroacetyl-derivatives by treatment with hexachloroacetone under mild conditions.Although secondary aromatic N-methylamines are unaffected by hexachloroacetone, saturated heterocyclic amines react vigorously.A mechanistic study using 2-amino-4-t-butylthiazole showed that the reaction is first order in hexachloroacetone, second order in amine, and base-catalysed; there is no appreciable kinetic isotope (H/D) effect nor accumulation of intermediates during the reaction.A sequence which accommodates these results is suggested.