42571-81-3

Usage

InChI:InChI=1/C10H11ClO2/c1-7(2)8-5-3-4-6-9(8)13-10(11)12/h3-7H,1-2H3

Upstream product

• 88-69-7 2-(1-methylethyl)phenol 
• 32315-10-9 bis(trichloromethyl) carbonate 

Downstream Products

• 2077-13-6 2-chlorocumene 
• 42571-33-5 C₁₉H₁₉N₃O₂ 
• 42571-30-2 C₁₉H₂₂N₂O₂ 
• 42571-29-9 C₂₂H₂₈N₂O₂ 
• 42571-27-7 C₂₄H₃₂N₂O₂ 
• 42571-32-4 C₁₈H₁₇Cl₃N₂O₂ 
• 42571-25-5 C₂₁H₂₆N₂O₂ 
• 42571-28-8 C₂₀H₂₄N₂O₂ 
• 42571-35-7 C₁₉H₂₂N₂O₂ 
• 42571-17-5 C₁₉H₂₁ClN₂O₂ 
• 42571-26-6 C₂₀H₂₄N₂O₂ 

Relevant academic research and scientific papers

Versatile Cp*Co(III)(LX) Catalyst System for Selective Intramolecular C-H Amidation Reactions

Herein, we report the development of a tailored cobalt catalyst system of Cp*Co(III)(LX) toward intramolecular C-H nitrene insertion of azidoformates to afford cyclic carbamates. The cobalt complexes were easy to prepare and bench-stable, thus offering a convenient reaction protocol. The catalytic reactivity was significantly improved by the electronic tuning of the bidentate LX ligands, and the observed regioselectivity was rationalized by the conformational analysis and DFT calculations of the transition states. The superior performance of the newly developed cobalt catalyst system could be broadly applied to both C(sp2)-H and C(sp3)-H carbamation reactions under mild conditions.

Visible-Light-Induced Intramolecular C(sp2)-H Amination and Aziridination of Azidoformates via a Triplet Nitrene Pathway

Catalytic intramolecular C-H amination and aziridination reactions of o-allylphenyl azidoformates have been achieved under visible-light irradiation, providing a mild, clean, and efficient method for the synthesis of useful benzoxazolones and [5.1.0] bicyclic aziridines. Mechanistic studies suggest that a triplet nitrene acts as the reactive intermediate. The chemoselectivity of the reaction, with alkyl olefin aziridination ? electron deficient olefin aziridination ≈ C(sp2)-H amination ? C(sp3)-H amination was observed, which may be instructive in the development of an understanding of visible-light-induced triplet nitrene transformation reactions.