42583-89-1Relevant academic research and scientific papers
Synthesis of iodine-131 labeled 6β-iodomethyl-19-norsitost-5(10)-en-3β-ol and 19-iodositost-5-en-3β-ol for adrenal imaging
Komatsu,Yamauchi,Shimoirisa,Ito,Maeda,Kojima
, p. 339 - 345 (1979)
6β-Iodomethyl-19-norsitost-5(10)-en-3β-ol (V) was synthesized by homoallylic rearrangement of 19-iodositost-5-en-3β-ol (IV), which was obtained by the hydrolysis of 19-iodotost-5-en-3β-ol acetate (III) derived from the displacement of sitost-5-ene-3β,19-diol 3-acetate 19-p-toluenesulfonate (I) with sodium iodide in isopropanol. The radioiodinated IV and V were prepared by isotope exchange with sodium iodide-I-131.
