4262-04-8

Usage

General Description

2-[(pyridin-3-ylmethyl)sulfanyl]pyridine is a chemical compound with the molecular formula C11H9N3S. It is a pyridine-based compound that contains a sulfur atom attached to the 3-position of one of the pyridine rings. This chemical is often used as a building block in organic synthesis and can be found in a variety of research applications, such as in the development of pharmaceuticals and agrochemicals. It has the potential to exhibit biological activity due to its unique structure, and it can be modified to create analogs with different properties for use in various fields of study. Overall, 2-[(pyridin-3-ylmethyl)sulfanyl]pyridine is a versatile compound with potential applications in diverse scientific and industrial processes.

Upstream product

• 2637-34-5 2-Sulfanylpyridine 
• 6959-48-4 3-chloromethylpyridinium chloride 
• 109-09-1 2-chloropyridine 
• 100-55-0 3-hydroxymethylpyridin 
• 2637-34-5 pyridine-2-thione 

Downstream Products

• 128802-93-7 1-(2-pyridyl)-1-(3-pyridyl)methane 

Relevant academic research and scientific papers

Promoting Effect of Crystal Water Leading to Catalyst-Free Synthesis of Heteroaryl Thioether from Heteroaryl Chloride, Sodium Thiosulfate Pentahydrate, and Alcohol

It is observed the crystal water in sodium thiosulfate pentahydrate (Na2S2O3·5H2O) can promote its multicomponent reaction with heteroaryl chlorides and alcohols, providing a facile, green, and specific synthesis of unsymmetrical heteroaryl thioethers via one-step formation of two C-S bonds under catalyst-, additive-, and solvent-free conditions. Mechanistic studies suggest that the crystal water in Na2S2O3·5H2O is crucial in generating the key thiol intermediates and byproduct NaHSO4, which then catalyzes the dehydrative substitution of alcohols with thiols to afford thioethers.

Versatile C(sp2)?C(sp3) Ligand Couplings of Sulfoxides for the Enantioselective Synthesis of Diarylalkanes

The reaction of chiral (hetero)aryl benzyl sulfoxides with Grignard reagents affords enantiomerically pure diarylalkanes in up to 98 % yield and greater than 99.5 % enantiomeric excess. This ligand coupling reaction is tolerant to multiple substitution patterns and provides access to diverse areas of chemical space in three operationally simple steps from commercially available reagents. This strategy provides orthogonal access to electron-deficient heteroaromatic compounds, which are traditionally synthesized by transition metal catalyzed cross-couplings, and circumvents common issues associated with proto-demetalation and β-hydride elimination.

2-pyrimidine Derivatives: New Bronchosecretolytic Agents

2-pyrimidine derivatives (1a-n) promote the excretion of phenol red into the mouse trachea, indicating an increased tracheobronchial secretion.Furthermore, 2-pyrimidine (1a) (tasuldine) produces greater ex