4264-28-2

Basic information

• Product Name: 2-phenyl-1H-indol-3-yl 4-methylbenzenesulfonate
• Synonyms: 2-phenyl-1H-indol-3-yl 4-methylbenzenesulfonate
• CAS NO: 4264-28-2
• Molecular Weight: 363.437
• Mol File: 4264-28-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-phenyl-1H-indol-3-yl 4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-1H-indol-3-yl 4-methylbenzenesulfonate(4264-28-2)
• EPA Substance Registry System: 2-phenyl-1H-indol-3-yl 4-methylbenzenesulfonate(4264-28-2)

Safety Data

• Hazardous Substances Data: 4264-28-2(Hazardous Substances Data)

Upstream product

• 120-46-7 1,3-diphenylpropanedione 
• 199277-23-1 1-azido-2-(phenylethynyl)benzene 
• 104-15-4 toluene-4-sulfonic acid 
• 1859-39-8 2-phenyl-N-hydroxyindole 
• 98-59-9 p-toluenesulfonyl chloride 
• 670-80-4 4-cyclohexen-1-ylmorpholine 

Downstream Products

• 2989-63-1 2-phenyl-3H-indol-3-one 

Relevant articles and documents

Synthesis of 1: H -indole-3-sulfonates via palladium-catalyzed tandem reactions of 2-alkynyl arylazides with sulfonic acids

An efficient method for the synthesis of 1H-indole-3-sulfonates via palladium-catalyzed tandem reactions of 2-alkynyl arylazides with sulfonic acids has been developed. The desired products were obtained in good to excellent yields under mild reaction con

Pd-Catalyzed One-Pot Insertion Reaction of Cyclic C-Acylimines into Carbon-Carbon σ-Bonds for the Synthesis of Polyfunctional Indolin-3-ones from 2-Alkynyl Arylazides and Aryl Ketones

A method to prepare polyfunctional indolin-3-ones by Pd-catalyzed one-pot insertion reaction of cyclic C-acylimines into carbon-carbon σ-bonds is described. The reaction was accomplished in good to excellent yields under mild reaction conditions. (Figure presented.).

STUDIES ON TERTIARY AMINE OXIDES. LXXII. SOME NUCLEOPHILIC REACTIONS OF 1-HYDROXY-2-PHENYLINDOLE

1-Hydroxy-2-phenylindole (1) reacts with tosyl chloride and p-nitrobenzenesulfonyl chloride in DMF-pyridine to give the corresponding 2-phenyl-3-sulfonyloxyindole (2 and 4).Benzoyl chloride is less reactive, and 1-benzoyloxy-2-phenylindole (5) or 3-benzoyloxy-2-phenylindole (6) is formed, depending upon the reaction conditions. 3-Acetoxy-2-phenylindole (7) is also obtained by refluxing 1 with acetic anhydride or with acetyl chloride in DMF-pyridine.Treatment of 1 with tosyl chloride and then with 1-morpholinocyclohexene (9), ethyl acetoacetate (17) and ethyl cyanoacetate (20) in DMF-pyridine at room temperature affords 3-(2-oxocyclohexyl)-2-phenylindole (10), ethyl α-(2-phenyl-3-indolyl)acetoacetate (18) and ethyl α-(2-phenyl-3-indolyl)cyanoacetate (21) in 23.2, 41 and 61percent yields, respectively.Keywords: enehydroxylamine system; 1-acyloxy-2-phenylindole; 3-acyloxy-2-phenylindole; 1-morpholinocyclohexene; 3-(2-oxocyclohexyl)-2-phenylindole; ethyl α-(2-phenyl-3-indolyl)acetoacetate; ethyl α-(2-phenyl-3-indolyl)cyanoacetate