426823-03-2Relevant academic research and scientific papers
Chiral 1,2,3,4-tetrahydroquinolinyl-oxazoline ligands for Ru-catalyzed asymmetric transfer hydrogenation of ketones
Zhou, Yi-Bo,Tang, Fang-Yi,Xu, Hua-Dong,Wu, Xin-Yan,Ma, Jun-An,Zhou, Qi-Lin
, p. 469 - 473 (2007/10/03)
Chiral 1,2,3,4-tetrahydroquinolinyl-oxazoline compounds have been synthesized from 8-quinolinecarboxylic acid and enantiomerically pure amino alcohols using a convenient procedure. Asymmetric transfer hydrogenation of aryl ketones with the catalyst prepared in situ from [Ru(p-cymene)Cl2]2 and ligands 2 in 2-propanol in the presence of KOH, afforded the corresponding secondary alcohols in reasonable yields and up to 83% e.e.
